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Calcium Channel Blockers [PDF]
Calcium channel blockers are widely used in the treatment of ischemic heart disease, hypertension, and supraventricular tachycardia. The prototype agents, verapamil, nifedipine, and diltiazem, represent three classes of calcium channel blockers, each of which has different pharmacologic effects.
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Journal of Pharmacy Practice, 1990
Calcium is an integral component in numerous physiological processes and functions. As such, drugs that interfere with the movement of calcium into or out of cells, or the activity of intracellular calcium are useful in treating a variety of disease states.
Patricia Bartlomé+2 more
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Calcium is an integral component in numerous physiological processes and functions. As such, drugs that interfere with the movement of calcium into or out of cells, or the activity of intracellular calcium are useful in treating a variety of disease states.
Patricia Bartlomé+2 more
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Calcium channel blockers and asthma
Lung, 1986An increase in cytoplasmic Ca++ concentration can activate not only respiratory smooth muscles, but also mast cells, bronchial mucus glands, and the vagi. Altered control of cytoplasmic Ca++ may also be related to the development of bronchial hyperreactivity.
So, SY, Ip, M, Lam, WK
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Calcium channel blockers and cancer
The American Journal of Medicine, 2000We sought to explore the relation that has been previously reported between calcium channel blockers and an increased risk of cancer.We followed 3,511 participants, age 65 years or older, in the Duke Established Populations for Epidemiologic Studies of the Elderly for up to 10 years.
Joseph T. Hanlon+6 more
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Calcium channel blockers and calcium channels
2004In 1883, Ringer showed that to get isolated hearts to contract, it was necessary to have Ca2+ ions in the perfusion medium [421]. This was the first demonstration of the critical role of calcium in cellular activity. Remarkably, a hundred years passed before the importance of calcium was recognized in processes other than muscle contraction, and almost
Theophile Godfraind, Eric A. Ertel
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Calcium channel blockers in psychiatry
Psychosomatics, 1987Abstract Calcium channel blockers have an established role in the treatment of various cardiovascular disorders and potential applications in psychiatry. Preliminary reports based on limited numbers of patients indicate that they are promising for mania, of uncertain utility for depression or schizophrenia, and deserving of further investigation for ...
Jerrold F. Rosenbaum+2 more
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