Results 311 to 320 of about 411,380 (346)

Models of calcium permeation through T-type channels

Pflügers Archiv - European Journal of Physiology, 2014
Ca(2+) entry is indispensable part of intracellular Ca(2+) signaling, which is vital for most of cellular functions. Low voltage-activated (LVA or T-type) calcium channels belong to the family of voltage-gated calcium channels (VGCCs) which provide Ca(2+) entry in response to membrane depolarization.
openaire   +2 more sources

First pharmacophoric hypothesis for T-type calcium channel blockers

Bioorganic & Medicinal Chemistry, 2004
A three-dimensional pharmacophore model was developed for T-type calcium channel blockers in order to map common structural features of highly active compounds by using CATALYST program. In the absence of three dimensional structure based information like binding mode and unavailability of more number of specific T-type calcium channel blockers, this ...
Munikumar Reddy, Doddareddy, Hee Kyung, Jung, Jae Yeol, Lee, Yong Sup, Lee, Yong Seo, Cho, Hun Yeong, Koh, Ae Nim, Pae   +6 more
openaire   +2 more sources

Molecular physiology of low-voltage-activated t-type calcium channels.

Physiological Reviews, 2003
E. Perez-Reyes
semanticscholar   +1 more source

Pharmacology and Drug Discovery for T-Type Calcium Channels

CNS & Neurological Disorders - Drug Targets, 2006
Voltage-gated calcium channels are found in the plasma membrane of many excitable and non-excitable cells. When open, they permit influx of calcium, which acts as a second messenger to initiate diverse physiological cellular processes. Ten unique alpha1 subunits, grouped in three families (CaV1, CaV2, and CaV3), encode biophysically and ...
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T-Type Calcium Channel

2022
openaire   +1 more source

T-Type Calcium Channels in Epilepsy

2022
Anne-Sophie Sack, Terrance P. Snutch
openaire   +1 more source

T-type calcium channels: From molecule to therapeutic opportunities.

International Journal of Biochemistry and Cell Biology, 2019
N. Weiss, G. Zamponi
semanticscholar   +1 more source

Achievements, Challenges, and Prospects of Calcium Batteries

Chemical Reviews, 2020
Elena Arroyo-de Dompablo, Alexandre Ponrouch, Patrik Johansson   +2 more
exaly  

T-Type voltage gated calcium channels: a target in breast cancer?

Breast Cancer Research and Treatment, 2018
Anamika Bhargava, S. Saha
semanticscholar   +1 more source

Critical role of Cav3.2 T-type calcium channels in the peripheral neuropathy induced by bortezomib, a proteasome-inhibiting chemotherapeutic agent, in mice.

Toxicology, 2019
Shiori Tomita, F. Sekiguchi, Tomoyo Deguchi, Takaya Miyazaki, Yuya Ikeda, Maho Tsubota, S. Yoshida, H. D. Nguyen, Takuya Okada, N. Toyooka, A. Kawabata   +10 more
semanticscholar   +1 more source