Results 131 to 140 of about 503,305 (349)

Tumor Suppression by a Proapoptotic Calcium-activated Chloride Channel in Mammary Epithelium [PDF]

, 2001
Randolph C. Elble, Bendicht U. Pauli
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Intermediate‐conductance calcium‐activated potassium channels participate in neurovascular coupling [PDF]

, 2011
Thomas A. Longden, KM Dunn, HJ Draheim, Mark T. Nelson, Weston Ah, G. Edwards   +5 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Islet Oxygen Consumption and Insulin Secretion Tightly Coupled to Calcium Derived from L-type Calcium Channels but Not from the Endoplasmic Reticulum [PDF]

, 2008
Merle L. Gilbert, Seung-Ryoung Jung, Benjamin J. Reed, Ian R. Sweet   +3 more
openalex   +1 more source

Effects of axotomy on calcium influx in reticulospinal neurons of larval lamprey [abstract] [PDF]

, 2007
only availableThe lamprey is a prime example of the remarkable axonal regeneration that can occur in lower vertebrates. Previous studies showed that spinal cord transected lamprey recover normal locomotor behavior in about 8 weeks (McClellan, 1998). With
Cozad, Matthew, McClellan, Andrew
core  

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Calcium channel blockade reduces mechanical strain-induced extracellular matrix gene response in lamina cribrosa cells [PDF]

, 2015
Barry Quill, Mustapha Irnaten, Neil G. Docherty, Elizabeth McElnea, Deborah Wallace, Abbot F. Clark, Colm O’Brien   +6 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The multifaceted role of calcium signaling dynamics in neural cell proliferation and gliomagenesis

AIMS Biophysics
Calcium (Ca2+) signaling plays a pivotal role in coordinating neural stem cell (NSC) proliferation across various cell cycle stages, regulating immediate early gene transcription, and governing processes like quiescence and cell division.
Ola A Al-Ewaidat , Sopiko Gogia, Valiko Begiashvili, Moawiah M Naffaa   +3 more
doaj   +1 more source