Results 131 to 140 of about 3,686,002 (351)
, 2020 Duncan, Randall L.Bone is a dynamic, living tissue that serves many functions throughout the body, including locomotion, protection of vital organs, and mineral homeostasis.
Gregory, Case
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Acta Neuropathologica Communications, 2019 Perioperative sleep disturbance is a risk factor for persistent pain after surgery. Clinical studies have shown that patients with insufficient sleep before and after surgery experience more intense and long-lasting postoperative pain.
Qi Li +9 more
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Calcium-permeable ion channels in control of autophagy and cancer
Frontiers in Physiology, 2013 Autophagy, or cellular self-eating, is a tightly regulated cellular pathway the main purpose of which is lysosomal degradation and subsequent recycling of cytoplasmic material to maintain normal cellular homeostasis.
Artem eKondratskyi +5 more
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Regulation of CaV2 calcium channels by G protein coupled receptors
Biochimica et Biophysica Acta, 2012 Voltage gated calcium channels (Ca2+ channels) are key mediators of depolarization induced calcium influx into excitable cells, and thereby play pivotal roles in a wide array of physiological responses.
G. Zamponi, K. Currie
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines.
, 2000 The pharmacology of hSK1, a small conductance calcium-activated potassium channel, was studied in mammalian cell lines (HEK293 and COS-7). In these cell types, hSK1 forms an apamin-sensitive channel with an IC(50) for apamin of 8 nM in HEK293 cells and ...
Shah, M, Haylett, DG
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FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Cooperative calcium and zinc signaling underlies oxidant-induced neuronal injury [PDF]
, 2013 Intracellular zinc release triggered by oxidative injury leads to cellular K+ efflux and neuronal apoptosis. Low intracellular K+ enables protease and nuclease activation during cell death processes. Our laboratory has demonstrated that the reduction in
McCord, Meghan
core
, 2000 Kurtz R, Dürr V, Egelhaaf M. Dendritic calcium accumulation associated with direction-selective adaptation in visual motion-sensitive neurons in vivo. Journal of Neurophysiology.
Egelhaaf, Martin ; https://orcid.org/ +6 more
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CellsCalcium (Ca2+) signalling is a fundamental cellular process, essential for a wide range of physiological functions. It is regulated by various mechanisms, including a diverse family of Ca2+-binding proteins (CaBPs), which are structurally and ...
Vanessa S. Morris +4 more
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