Results 41 to 50 of about 521,104 (295)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Evaluation of Salicylic Acid and Calcium Chloride Effect on Shelf Life, Quality Properties and Antioxidant Activity of Peach Fruit cv. Amesden after Harvest

open access: yesMajallah-i ̒Ulum-i Bāghbānī, 2015
In order to evaluate the effect of different concentrations of postharvest salicylic acid and calcium chloride on shelf life, quality characteristics and antioxidant activity of peach fruit cv.
Gh. Davarynejad   +3 more
doaj   +1 more source

Growing single crystals in silica gel [PDF]

open access: yes, 1970
Two types of chemical reactions for crystal growing are discussed. The first is a metathetical reaction to produce calcium tartrate tetrahydrate crystals, the second is a decomplexation reaction to produce cuprous chloride ...
Rubin, B.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

CLCA2 is a positive regulator of store-operated calcium entry and TMEM16A. [PDF]

open access: yesPLoS ONE, 2018
The Chloride Channel Accessory (CLCA) protein family was first characterized as regulators of calcium-activated chloride channel (CaCC) currents (ICaCC), but the mechanism has not been fully established. We hypothesized that CLCAs might regulate ICaCC by
Aarushi Sharma   +4 more
doaj   +1 more source

Modulation of Lysosomal Cl Mediates Migration and Apoptosis through the TRPML1 as a Lysosomal Cl Sensor

open access: yesCells, 2023
Lysosomes are responsible for protein degradation and clearance in cellular recycling centers. It has been known that the lysosomal chloride level is enriched and involved in the intrinsic lysosomal function.
Dongun Lee, Jeong Hee Hong
doaj   +1 more source

A note on the effect of calcium alginate coating on quality of refrigerated strawberries. [PDF]

open access: yes, 2010
peer-reviewedAn alginate-based edible coating was investigated for the preservation of the quality of strawberries during cold storage (5 °C). Strawberries were immersed, successively, in sodium alginate and calcium chloride solutions to generate a ...
Ehsani, M.R.   +5 more
core  

secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]

open access: yes, 2019
Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J.   +6 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Evaluation of Deicer Impacts on Pervious Concrete Specimens (Phase II) [PDF]

open access: yes, 2018
This research examined the chemical degradation of pervious concrete due to calcium chloride or magnesium chloride deicers. The project consisted of Phase I, Phase IIa, and Phase IIb.
Almeida, Nara   +3 more
core  

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