Results 91 to 100 of about 595,184 (334)
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
A Technique for Making Nuclear Fusion in Solids [PDF]
, 2017 A technique is described for making nuclear fusion at room temperature by compressing a powder mixture comprising a deuteride and catalytic material. The result is explosive beyond known chemical reaction for the materials.
WAYTE, RICHARD
core +1 more source
Calcium Permeable Channels in Cancer Hallmarks
Frontiers in Pharmacology, 2020 Cancer, the second cause of death worldwide, is characterized by several common criteria, known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death resistance, angiogenesis, invasion and metastasis.
Sendoa Tajada, Carlos Villalobos
doaj +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Calcium phosphate crystal forms in human jaw bones of changed osteoporotic structure [PDF]
Stomatološki glasnik Srbije, 2011 Introduction. Calcium phosphates are chemical compounds that can be found in various forms within nature, as well as in human jaws and bones. The aim of this study was to assess the structure of solid chemical compounds which form the structure of ...
Poštić Srđan D.
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Estimation of corrosion resistance of curing mixtures based on coal-bearing rocks from Western Donbass [PDF]
, 2016 Purpose. Substantiation of possible use of coal-bearing rocks as a replacement for a part of the filler in the preparation of shotcrete for lining of mine workings in the conditions of mineralized mine water. Methods.
Harkusha, V, Kovalenko, V
core +2 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Predicting calcium in grape must and base wine by FT-NIR spectroscopy [PDF]
, 2018 Calcium content in sparkling wines may not exceed 80 mg/L due to the risk of aggregation with alginate capsules. The high calcium content usually found in wine and must emphasizes the need to develop alternative and appropriate techniques faster and ...
Barroso, João M. +4 more
core +1 more source