Results 151 to 160 of about 595,184 (334)
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Lignosulfonate as a Strength Additive for Non-Wood Paperboard [PDF]
, 2000 Recycle mills that use old corrugated cardboard (OCC) in their furnish experience difficulties in maintaining the quality of the paperboard produced. Recycle mills using the OCC collect their OCC from many parts of the world.
Martin, Francisco L.
core +1 more source
Characteristics and in vitro coagulation property of structured calcium compounds from cuttlebone
Food Chemistry: XCuttlebone, an underutilized byproduct of cuttlefish, remains largely unexplored regarding its properties. This study investigates the characteristics and in vitro coagulation properties of structured calcium compounds derived from cuttlebone.
Saranporn Khoseang +7 more
doaj
Exotic compounds of monovalent calcium synthesized at high pressure
Matter and Radiation at ExtremesIt is well known that atoms of the same element in different valence states show very different chemical behaviors. Calcium is a typical divalent metal, sharing or losing both of its valence electrons when forming compounds.
Jun Kong +5 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
On the quantitative thermogravimetric analysis of calcite content in hydrated cementitious systems [PDF]
, 2017 Calcite is a compound that is present in hydrated cementitious materials when carbonation of portlandite occurs or when limestone constituents are used.
De Belie, Nele +3 more
core +1 more source
Evaluation of endogenous compounds pharmacokinetics as illustrated by calcium
Регуляторные исследования и экспертиза лекарственных средств, 2018 The article reviews scientific literature on the conduct of in vivo pharmacokinetic studies of drugs that are similar to endogenous compounds. It summarises approaches to pharmacokinetic evaluation of calcium drugs.
N. N. Eremenko +2 more
doaj
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
The Relative Utilization of Certain Calcium Compounds by the Growing Chick
, 1929 Gregory D. Buckner +2 more
openalex +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source