Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures [PDF]
, 2014 The basic mechanisms by which strontium ranelate acts on bone are still unclear. We show that an important action of strontium salts is to block calcification in cultures of osteoblasts, the bone-forming cells.
A Barbara +44 more
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Transient increases in intracellular calcium and reactive oxygen species levels in TCam-2 cells exposed to microgravity [PDF]
, 2017 The effects of microgravity on functions of the human body are well described, including alterations in the male and female reproductive systems. In the present study, TCam-2 cells, which are considered a good model of mitotically active male germ cells,
Catizone, A +5 more
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Frontiers in Cardiovascular Medicine, 2021 Introduction: Donation after circulatory death (DCD) could substantially improve donor heart availability. In DCD, the heart is not only exposed to a period of warm ischemia, but also to a damaging pre-ischemic phase.
Maria Arnold +19 more
doaj +1 more source
Reduction of myocardial infarction by postischemic administration of the calpain inhibitor A-705253 in comparison to the Na(+)/H(+) exchange inhibitor Cariporide (R) in isolated perfused rabbit hearts [PDF]
, 2008 The calpain inhibitor A-705253 and the Na(+)/H(+) exchange inhibitor Cariporide (R) were studied in isolated perfused rabbit hearts subjected to 60 min occlusion of the ramus interventricularis of the left coronary artery (below the origin of the first ...
Bardenheuer H. +19 more
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Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium [PDF]
, 2013 Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such
A Gnoni +72 more
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A fluorometric method for the assay of protein kinase activity [PDF]
, 2018 Protein kinases constitute one of the largest protein families in nature. Current methods to assay their activity involve the use of radioactive ATP or very expensive reagents.
Figueroa, Carlos Maria +4 more
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Indonesian Journal of Obstetrics and Gynecology, 2022 Background. Gonadotropin-releasing hormone (GnRH) agonist widely used to induce hypoestrogenic climate overcoming any benign gynecologic abnormalities such as endometriosis, adenomyosis, or various cause of abnormal uterine bleeding. Hypoestrogenic cause
Enrico Hervianto +3 more
doaj +1 more source
Lactate signalling regulates fungal β-glucan masking and immune evasion [PDF]
, 2016 AJPB: This work was supported by the European Research Council (STRIFE, ERC- 2009-AdG-249793), The UK Medical Research Council (MR/M026663/1), the UK Biotechnology and Biological Research Council (BB/K017365/1), the Wellcome Trust (080088; 097377).
A Hopke +50 more
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Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]
, 2016 Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E. +5 more
core +1 more source
In vitro evaluation of soft drinks containing calcium lactate
Journal of Indian Association of Public Health Dentistry, 2018 Introduction: Over the past 2 years, the soft drink industry has seen a value growth of 11%. In total, 1.3 billion people in India drink nearly 5.9 billion liters of soft drinks per year making it one of the highest soft drink-consuming countries in the ...
Arun R Nair +4 more
doaj +1 more source