Results 101 to 110 of about 380,936 (322)

Calcium-Phosphate Metabolism Disorders in Patients with Renal Failure Clinical Significance, Diagnosis and Treatment

, 2019
Chronic kidney diseases (CKD) are commonly associated with calcium and phosphorus metabolism disorders. The general term of “renal osteodystrophy” (ROD) encompasses a complex spectrum of abnormalities in bone and mineral metabolism in CKD. This is one of
Kundurzhiev A., Grozeva V.
core   +1 more source

Dynamics of Bone Metabolism Markers Serum Level in Children with Bronchial Asthma on the Background of Vitamin D3 and Calcium Salt Supplementation

Zdorovʹe Rebenka, 2016
The aim: to optimize the diagnosis of the calcium-phosphorus metabolism disorders and to control the effectiveness of therapeutic and prophylactic use of vitamin D and calcium in children with bronchial asthma. Materials and methods.
A.O. Vertehel, L.S. Ovcharenko, T.H. Andriienko, I.V. Samokhin, O.V. Kriazhev   +4 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Gonadotropin-Releasing Hormone and the Urinary System: Analyzing Contradictory Findings of Efficacy and Safety Studies (Review)

Безопасность и риск фармакотерапии
INTRODUCTION. Gonadotropin-releasing hormone (GnRH) products are used to treat reproductive system disorders both in females (for temporary medically induced menopause) and males (in order to suppress certain functions in benign and malignant diseases ...
I. V. Maiborodin, B. V. Sheplev, E. S. Chernomortseva, I. Yu. Fedina, V. I. Maiborodina   +4 more
doaj   +1 more source

Bone mineral disorder in chronic kidney disease: Klotho and FGF23; cardiovascular implications

Nefrología (English Edition), 2016
Cardiovascular factors are one of the main causes of morbidity and mortality in patients with chronic kidney disease. Bone mineral metabolism disorders and inflammation are pathological conditions that involve increased cardiovascular risk in chronic ...
Laura Salanova Villanueva, Carmen Sánchez González, José Antonio Sánchez Tomero, Abelardo Aguilera, Esther Ortega Junco   +4 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify muscle types in a diet-independent and fiber-type unrelated way [PDF]

, 2010
Background The mouse skeletal muscle is composed of four distinct fiber types that differ in contractile function, number of mitochondria and metabolism. Every muscle type has a specific composition and distribution of the four fiber types. To find novel
Boekschoten, M.V., Mariman, E.C.M., Egbert Smit, Hulshof, M.F., Wilde, J., de, Edwin CM Mariman, Smit Egbert, Mark V Boekschoten, de Wilde, J., Janneke de Wilde, Mariman Edwin CM, de Groot, P.J., de Wilde Janneke, de Groot Philip, Smit, E., Philip de Groot, Groot, P.J., de, Boekschoten Mark V, Martijn FM Hulshof, Hulshof Martijn FM, Hulshof, M.F.M., de Groot, P.   +21 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Narusheniya metabolizma vitamina D pri ozhirenii

Ожирение и метаболизм, 2011
In this review we highlight the pathogenesis of vitamin D deficiency, the development of secondary hyperparathyroidism in obesity and after malabsorptive bariatric surgery.

doaj   +1 more source