Five patients with disorders of calcium metabolism presented with GCM2 gene variants
Scientific Reports, 2021 The GCM2 gene encodes a transcription factor predominantly expressed in parathyroid cells that is known to be critical for development, proliferation and maintenance of the parathyroid cells.
Alejandro García-Castaño +18 more
doaj +1 more source
Estimating the avoidable burden of certain modifiable risk factors in osteoporotic hip fracture using Generalized Impact Fraction (GIF) model in Iran [PDF]
, 2013 Backgrounds: The number of hip fractures, the most common complication of osteoporosis, has increased rapidly over the past decades. The goal of this study is to estimate the avoidable burden of certain modifiable risk factor of the condition using the ...
Aghamaleki, A. +9 more
core +1 more source
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
core +5 more sources
Calcium metabolism and mental disorder [PDF]
Psychological Medicine, 1977 This is an uncertain, neglected and misunderstood corner of organic psychiatry. Calcium disturbances are clinically the concern of physicians interested in bone diseases, in malabsorption or nutritional deficiencies, and opinions vary on whether such illnesses are accompanied by emotional and behavioural disorder: at least psychiatrists are not usually
openaire +2 more sources
Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories. [PDF]
, 2016 Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Adibhatla +148 more
core +1 more source
Disorders of Calcium and Phosphorus Metabolism and the Proteomics/Metabolomics-Based Research
Frontiers in Cell and Developmental Biology, 2020 Since calcium and phosphorus play vital roles in a multitude of physiologic systems, disorders of calcium and phosphorus metabolism always lead to severe consequences such as skeletal-related and cardiovascular morbidity, or even life-threatening ...
Meiheng Sun +27 more
doaj +1 more source
Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function [PDF]
, 2009 Background Human S100A12 is a member of the S100 family of EF-hand calcium-modulated proteins that are associated with many diseases including cancer, chronic inflammation and neurological disorders.
Moroz, Olga V. +13 more
core +2 more sources
Endocrine Connections, 2017 Background: X-linked hypophosphatemic rickets (XLHR) is due to mutations in PHEX leading to unregulated production of FGF23 and hypophosphatemia. XLHR is characterized by leg bowing of variable severity.
A Gizard +7 more
doaj +1 more source
Status of Serum Calcium, Phosphorus, Magnesium and Copper in Hypothyroid Patients- A Case Control Study [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: Thyroid disorders are the most common endocrine abnormality in the world secondary to diabetes mellitus. Thyroid hormones are essential for growth, neuronal development, reproduction and regulation of energy metabolism.
Diana Athokpham +2 more
doaj +1 more source
Metabolism of vitamin D, Calcium and Phosphorus and their disorders in goats [PDF]
Науковий вісник ветеринарної медицини, 2023 The review article presents materials on the metabolism of the mostcommon vitamins of group D ergocalciferol (D2), cholecalciferol (D3), aswell as essential macronutrients Ca and Phosphorus and their disorders ingoats.
Sakhniuk V., Hotsuliak M.
doaj +1 more source