Results 61 to 70 of about 1,428,474 (301)

French national diagnosis and care protocol (PNDS) for infantile idiopathic hypercalcemia (IIH)

Orphanet Journal of Rare Diseases
The objective of this study was to establish a French National Diagnosis and Care Protocol (PNDS: Protocole National de Diagnostic et de Soins), with the aim of providing health professionals with free, open access synthesis on optimal management and ...
Cyril Amouroux, Valérie Porquet-Bordes, Elodie Adler, Yoan Le Goff, Justine Bacchetta, Jean Philippe Bertocchio, Gilles Cambonie, Marie Courbebaisse, Odile Dicky, Thomas Edouard, Barbara Girerd, Vincent Guigonis, Fairouz Halitim, Pascal Houiller, Agnès Linglart, Emeline Marquant, Denis Morin, Jean Pierre Salles, Anya Rothenbuhler   +18 more
doaj   +1 more source

Mucins and calcium phosphate precipitates additively stimulate cholesterol crystallization

Journal of Lipid Research, 1998
Human biliary mucin and calcium binding protein (CBP) influence formation of both calcium salt precipitates and cholesterol crystals and colocalize in the center of cholesterol gallstones.
A.A. van den Berg, J.D. van Buul, G.N.J. Tytgat, A.K. Groen, J.D. Ostrow   +4 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Medication for bone loss in female patients with anorexia nervosa: a systematic review and management algorithm

Eating and Weight Disorders
Purpose Anorexia Nervosa can have a major impact on bone health through low bone mass and bone loss. Considering the lack of consensual guidelines for the prevention and treatment of bone loss in this condition, a systematic review was performed to ...
Alexandra Loisel, Anne Li, Karine Briot, Marie-Rose Moro, Chantal Stheneur, Corinne Blanchet   +5 more
doaj   +1 more source

Use of genetic algorithms and gradient based optimization techniques for calcium phosphate precipitation [PDF]

, 2004
Phase equilibrium computations constitute an important problem for designing and optimizing crystallization processes. The Gibbs free energy is generally used as an objective function to find phase amount and composition at equilibrium. In such problems,
Montastruc, Ludovic, Azzaro-Pantel, Catherine, Pibouleau, Luc, Domenech, Serge   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effect of modified compound calcium phosphate cement on the differentiation and osteogenesis of bone mesenchymal stem cells

Journal of Orthopaedic Surgery and Research, 2017
Background The aim of this study is to evaluate the effect of self-invented compound calcium phosphate cement upon the proliferation and osteogenesis of bone mesenchymal stem cells (BMSCs).
Jican Zeng, Jiazhong Lin, Guanfeng Yao, Kangmei Kong, Xinjia Wang   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Protein-Bound Calcium Phosphate in Uremic Rat Serum: A Quantitative Study [PDF]

, 2020
Protein-bound calcium (prCa) constitutes about 40% of serum total calcium, in which albumin is the most dominant protein. Given the chemical interaction between calcium and phosphate (Pi), the increased serum Pi in chronic kidney disease may cause ...
Shu-Hu, Liu, Gang, Wu, Hong-Xing, Fan, Fan, Li, Tian-Lan, Zhang, Bao-Di, Gou, Yu-Xi, Gao   +6 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source