Results 91 to 100 of about 1,131,166 (283)

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

Advanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran, Kalyan Shobhana, Zlatan Trifunovic, Dan Smith, Michael Stuiber, Chennupati Jagadish, Mirella Dottori, Andrea J. O'Connor, Vini Gautam   +8 more
wiley   +1 more source

Electrochemical and biomimetic deposition of calcium phosphates on titanium alloys

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов
The presence of impurities of other metals in titanium alloys affects the composition of the oxide film after heat treatment: in addition to rutile, the VT 00 alloy contains Ti6O oxide, which in the VT 1-0 and VT 6 alloys is transformed into Ti3O oxide ...
A.E. Doroshenko, V.K. Krut’ko, O.N. Musskaya, A.I. Kulak   +3 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

A first look at the formation of PEO-PDA coatings on 3D titanium

ChemPhysMater
Additive manufacturing has revolutionized implantology by enabling the fabrication of customized, highly porous implants. Surface modifications using electrochemical methods can significantly enhance the bioactivity and biocompatibility of biomaterials ...
K.V. Nadaraia, D.V. Mashtalyar, M.A. Piatkova, A.I. Pleshkova, I.M. Imshinetskiy, M.S. Gerasimenko, E.A. Belov, G.A. Zverev, S.L. Sinebryukhov, S.V. Gnedenkov   +9 more
doaj   +1 more source

Fabrication of calcium phosphate coating on pure magnesium substrate via simple chemical conversion coating: surface properties and corrosion performance evaluations

Journal of Materials Research and Technology, 2019
The main objective of the current work was to fabricate calcium phosphate (CaP) coating on 99.9% purity magnesium, Mg substrate through simple chemical conversion method and evaluated the surface properties and corrosion performance of the coated ...
Mohd Amin Farhan Zaludin, Zul Azhar Zahid Jamal, Mohd Nazree Derman, Mohd Zaheruddin Kasmuin   +3 more
doaj   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Manufacture of nanosized apatite coatings on titanium with different surface treatments using a supersaturated calcification solution

Química Nova
The biomimetic method is used for the deposition of calcium phosphate coatings (Ca - P) on the surface of different biomaterials. However, the application of this method requires long exposure times in order to obtain a suitable layer thickness for its ...
Adrian Paz Ramos, Gabriel O. Ybarra, Leonardo M. Pazos, María B. Parodi, Laura Rodríguez, Mónica López Hernández, Jesús E. González Ruíz   +6 more
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source