Results 51 to 60 of about 1,131,166 (283)

State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications

open access: yesNanomaterials
The aim of this review is to investigate the possibility of fabricating coatings functionalized with bioactive molecules. These coatings are interesting when applied to biomedical devices, particularly in the orthopedic field. In fact, the application of
Matteo Montesissa   +5 more
doaj   +1 more source

Biomimetic fabrication of calcium phosphate/chitosan nanohybrid composite in modified simulated body fluids

open access: yeseXPRESS Polymer Letters, 2017
In this study, nucleation and growth of bone-like hydroxyapatite (HAp) mineral in modified simulated body fluids (m-SBF) were induced on chitosan (CS) substrates, which were prepared by spin coating of chitosan on Ti substrate.
K. H. Park   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Fabrication and Characterization of Titanium-doped Hydroxyapatite Thin Films [PDF]

open access: yes, 2007
Hydroxyapatite [Ca10(PO4)6(OH)2, HA] is used in many biomedical applications including bone grafts and joint replacements. Due to its structural and chemical similarities to human bone mineral, HA promotes growth of bone tissue directly on its surface ...

core   +4 more sources

Bioactive Calcium Phosphate Coatings for Bone Implant Applications: A Review

open access: yes, 2023
This review deals with the design of bioactive calcium phosphate coatings deposited on metallic substrates to produce bone implants. The bioceramic coating properties are used to create a strong bonding between the bone implants and the surrounding bone ...
Joël Fauré   +5 more
core   +1 more source

Long-Term Assessment of the In Vitro Corrosion Resistance of Biomimetic ACP Coatings Electrodeposited from an Acetate Bath

open access: yesJournal of Functional Biomaterials, 2021
Calcium phosphate coatings are able to improve the osseointegration process due to their chemical composition, which is similar to that of bone tissues.
Patrycja Osak   +4 more
doaj   +1 more source

Calcium phosphates formation on CaTiO3 coated titanium

open access: yesJournal of Materials Science: Materials in Medicine, 2007
In this study, performance of calcium phosphate formation of CaTiO3 coating film on Ti in Hanks' balanced saline solution (HBSS) was investigated. CaTiO3 thin films with a thickness of 50 nm were deposited on Ti using radiofrequency (RF) magnetron sputtering. The temperature of Ti substrate was adjusted to room temperature (RT) and 873 K.
Naofumi, Ohtsu   +4 more
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Recent progress in adhesion strength between calcium phosphate coatings and titanium implants

open access: yesKouqiang hemian waike zazhi
Calcium phosphate, due to its excellent biocompatibility and bioactivity, can be used as the implant coating to improve osseointegration. However, the calcium phosphate coating still faces problems such as exfoliating and insufficient adhesion strength ...
WANG Yuning, WANG Zuolin
doaj   +1 more source

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