Results 141 to 150 of about 1,747,741 (337)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Calcium Phosphate Bioceramics Prepared by Wet Chemical Precipitation Route

Due to excellent biocompatibility with living body and bioactivity, calcium phosphate (CaP) ceramics (hydroxylapatite [HAp, Ca10(PO4)6(OH)2)], β-tricalcium phosphate [β-TCP, Ca3(PO4)], biphasic calcium phosphates [BCP, β-TCP + HA]) are widely used as ...
Borodajenko, Natālija, Šalma-Ancāne, Kristīne, Bērziņa-Cimdiņa, Līga   +2 more
core  

Inhibition of Acid Phosphatase Enzyme Activity in the Presence of Noncrystalline Calcium Phosphate and Nanocrystalline Calcium Apatite: a Preliminary Study

, 2009
*Background* Our bones are remodelled repeatedly during life. A new and “healthy” bone tissue replaces the old one. Accordingly, the bone degrading cells, the osteoclasts, prefer old and fatigued bone.
Yassen Pekounov
core  

Electron diffraction and high resolution transmission electron microscopy in the characterization of calcium phosphate precipitation from aqueous solutions under biomineralization conditions

European Cells & Materials, 2001
Calcium phosphate precipitation obtained from aqueous solutions at room and body temperature and pH 5.5-7.5 were investigated by high-resolution transmission electron microscopy (HRTEM), transmission electron diffraction, scanning electron microscopy ...
Suvorova E. I., Buffat P. A.
doaj  

Clindamycin-Loaded Nanosized Calcium Phosphates Powders as a Carrier of Active Substances. [PDF]

Nanomaterials (Basel), 2023
Słota D, Piętak K, Florkiewicz W, Jampilek J, Tomala A, Urbaniak MM, Tomaszewska A, Rudnicka K, Sobczak-Kupiec A.   +8 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Release Kinetics of Monomers from Dental Composites Containing Fluoride-Doped Calcium Phosphates. [PDF]

Pharmaceutics, 2023
Alambiaga-Caravaca AM, López-Castellano A, Chou YF, Luzi A, Núñez JM, Banerjee A, Jovani Sancho MDM, Sauro S.   +7 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Synthesis Methodology and Investigation of Calcium Phosphate Biomaterials for Bone Tissue Replacement in Regenerative Medicine

The wet chemical precipitation method was chosen for synthesis of calcium phosphates. It is one of the methods to obtain calcium phosphates that demonstrate both complexity of the method from point of view of physical chemistry and variability of product
Sokolova, Marina, Stīpniece, Līga, Borodajenko, Natālija, Šalma-Ancāne, Kristīne, Dubņika, Arita   +4 more
core  

Evolving application of biomimetic nanostructured hydroxyapatite

Nanotechnology, Science and Applications, 2010
Norberto Roveri, Michele IafiscoLaboratory of Environmental and Biological Structural Chemistry (LEBSC), Dipartimento di Chimica ‘G. Ciamician’, Alma Mater Studiorum, Università di Bologna, Bologna, ItalyAbstract: By ...
Norberto Roveri, Michele Iafisco
doaj