Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Calcium sulfate exists in three forms, namely dihydrate or gypsum (CaSO4·2H2O), anhydrite (CaSO4), and hemihydrate or bassanite (CaSO4·0.5H2O) depending on temperature, pressure, pH, and formation conditions.
Reza Taherdangkoo +5 more
doaj +1 more source
Phosphorus Immobilization in Poultry Litter and Litter-amended soils with Aluminum, Calcium and Iron amendments [PDF]
Arkansas produces approximately one billion broilers each year. Phosphorous (P) runoff from fields receiving poultry litter is believed to be one of the primary factors affecting water quality in Northwest Arkansas.
Daniels, T. C. +2 more
core +2 more sources
An Experimental and Analytical Approach to Understanding the Dynamic Leaching from Municipal Solid Waste Combustion Residue [PDF]
This paper describes an experimental technique involving the use of small columns for generating significant quantities of leachate data from municipal solid waste (MSW) solid residues within a relatively short amount of time.
Gardner, Kevin H. +2 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Calcite moonmilk of microbial origin in the Etruscan Tomba degli Scudi in Tarquinia, Italy [PDF]
A white deposit covering the walls in the Stanza degli Scudi of the Tomba degli Scudi, Tarquinia, Italy, has been investigated. In this chamber, which is still preserved from any kind of intervention such as cleaning and sanitization, ancient Etruscans ...
Arrighi, Chiara +10 more
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Road Performance of Calcium Sulfate Whisker and Polyester Fiber Composite-Modified Asphalt Mixture
In order to better improve the practical engineering problems such as rutting, cracking, pit, and groove in highway engineering, the stability and strength characteristics of calcium sulfate whisker and polyester fiber in asphalt mixture are evaluated ...
Xiushan Wang, Bowen Dong, Junjie Wang
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Impact of Calcium Sources on Soil Chemical Properties, Tomato Growth, Yield, and Quality
Nigerian soils are generally light-textured and have a low cation exchange capacity, crucial for retaining exchangeable cations like calcium, which enhances tomato (Solanum lycopersicum L.) shelf life.
Aruna Olasekan Adekiya +5 more
doaj +1 more source

