Results 151 to 160 of about 906,408 (267)

Executive Summary of Evidence-Based Guidelines for the Diagnosis and Treatment of Pediatric CKD-Mineral and Bone Disorder (Version 2024). [PDF]

Kidney Int Rep
Wang M, Xiong HY, Zhu C, Yu X, Jiao J, Tan L, Shen Y, Xu H, Mao J, Zhou J, Jiang XY, Shen Q, Wang F, Huang S, Huang W, Xia ZK, Liu XR, Wang H, Wu YB, Yu L, Tao YH, Gao CL, Li YJ, Sun SZ, Zhang DF, Shao XS, Zhao LJ, Wang X, Dang XQ, Huang HM, Chen Y, Li Q, Zhang A, Subspecialty Group of Nephrology, the Society of Pediatrics, Chinese Medical Association.   +35 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Large-scale experimental investigation of biotreated sand column using different grouting pipe configurations. [PDF]

PLoS One
Wang C, Wei Z, Shi J, He X.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Evidence-Based Guidelines for the Diagnosis and Treatment of Pediatric CKD-Mineral and Bone Disorder (Version 2024). [PDF]

Kidney Int Rep
Wang M, Xiong HY, Zhu C, Yu X, Jiao J, Tan L, Shen Y, Xu H, Mao J, Zhou J, Jiang XY, Shen Q, Wang F, Huang S, Huang W, Xia ZK, Liu XR, Wang H, Wu YB, Yu L, Tao YH, Gao CL, Li YJ, Sun SZ, Zhang DF, Shao XS, Zhao LJ, Wang X, Dang XQ, Huang HM, Chen Y, Li Q, Zhang AH, Subspecialty Group of Nephrology, the Society of Pediatrics, Chinese Medical Association.   +35 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Astrocyte-Targeted Biomarkers for Calcitonin Gene-Related Peptide-Related Neurovascular Disorders: Insights from Calcium and Metabolic Profiling. [PDF]

ACS Omega
Phatruengdet T, Niraso B, Phiwchai I.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture. [PDF]

Front Synaptic Neurosci
Begley JC, Prüss H, Turko P, Dean C.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source