Results 141 to 150 of about 4,759,077 (364)

The Effect of Padlet on Nursing Students’ Drug Dose Calculation Skills [PDF]

open access: yes
Objective: Nursing students attended distance learning due to the pandemic, which made it more difficult for them to learn how to calculate the right dose because drug dose calculation requires constant practice.
Şule Bıyık Bayram
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

CLASSER CALCULER

open access: yesSens public, 2012
Un rêve, plus ou moins explicite, hante nos esprits depuis plusieurs millénaires. On le retrouve ci et là dans les listes égyptiennes, dans les catalogues aristotéliciens, dans le règles mnémotechniques des néoplatoniciens florentins de la renaissance, dans les constructions mathématiques de Leibniz, dans les affirmations des grands noms du web : le ...
openaire   +3 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

A survey of drug-dose calculation skills of Australian tertiary hospital doctors [PDF]

open access: yes, 2009
Objective: To assess the ability of doctors to calculate drug doses and their workplace prescribing and calculation habits. Design and setting: Prospective, questionnaire-based observational study conducted at a 570-bed teaching hospital in February ...
Lind, James F   +2 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Half a century of calculation in Western Australian secondary schools [PDF]

open access: yes, 2006
One person's observations about calculation over the lifetime of the Mathematical Association of Western Australia are briefly described. The noticeable shifts, as they have affected the teaching of mathematics, which include the means of calculation ...
Kissane, B.
core   +1 more source

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