Results 151 to 160 of about 166,028,341 (301)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

An introduction to the calculus of variations

, 1960
The development of the theory of the calculus of variations has from the beginning been closely connected with that of the differential and integral calculus.

core  

Functionals In The Calculus Of Variations

, 1970
This thesis deals with an introduction to the functionals in the calculus of variations. Since calculus of variations is a relatively advanced topic in mathematics, this thesis is written with the attempt to introduce some of the oasis notions with ...
Kao, Tsai-tse
core   +1 more source

Prevalence and Surgical Implications of Cystic Artery Variations in Calot's Triangle: A Prospective Observational Study. [PDF]

Cureus
Kothule BG, Dikle AM, Vairage KR.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Stone Between Crossed Paths: Retrograde Intrarenal Surgery for Isthmic Calculus in the Setting of Renal and Gut Malformations. [PDF]

Cureus
Reddy P, Korrapati VR, Yedulla Reddy R, Sekar H, Krishnamoorthy S.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Dental Caries Experience (DMFT) and Oral Hygiene Status Among 18-Year-Old Adolescents in Two Bulgarian Municipalities: A Cross-Sectional Study. [PDF]

Children (Basel)
Kondeva V, Stoeva V, Rimalovska S, Stoyanova R.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Retrograde intrarenal surgery in a non-fused left crossed ectopic kidney with large renal calculus: a case report and review of literature. [PDF]

Oxf Med Case Reports
Anwaar A, Haq IU, Khan AM, Hameed F, Akilimali A.   +4 more
europepmc   +1 more source