Results 141 to 150 of about 20,465 (306)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Calculus for Variations: MAP 515
, 2011 Calculus for Variations: MAP 515, degree examination May/June ...
Dukuza, K, Lubczonok, G L
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Calculus of Variations, Classical and Modern
, 2011 A. Blaquiere: Quelques aspects geometriques des processus optimaux.- C. Castaing: Quelques problemes de mesurabilite lies a la theorie des commandes.- L.
Conti, Roberto
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Functionals In The Calculus Of Variations
, 1970 This thesis deals with an introduction to the functionals in the calculus of variations. Since calculus of variations is a relatively advanced topic in mathematics, this thesis is written with the attempt to introduce some of the oasis notions with ...
Kao, Tsai-tse
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Application of Calculus of Variations [PDF]
, 2015 Title: Application of Calculus of Variations Author: Anton'ın Bohata Department: Department of Mathematics Education Supervisor: doc. RNDr. Jana Star'a, CSc., Department of Mathematical Analysis Abstract: The thesis deals with the calculus of variation ...
Bohata, Antonín
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Calculus of variations and optimal control
, 1998 The theory of a Pontryagin minimum is developed for problems in the calculus of variations. The application of the notion of a Pontryagin minimum to the calculus of variations is a distinctive feature of this book.
Milyutin, A A, Osmolovskii, N P
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A Characterization of Fields in the Calculus of Variations [PDF]
Proceedings of the National Academy of Sciences, 1932 Morse, Marston, Littauer, S. B.
openaire +3 more sources