Results 121 to 130 of about 20,567 (306)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Functionals In The Calculus Of Variations [PDF]

open access: yes, 1970
This thesis deals with an introduction to the functionals in the calculus of variations. Since calculus of variations is a relatively advanced topic in mathematics, this thesis is written with the attempt to introduce some of the oasis notions with ...
Kao, Tsai-tse
core   +1 more source

The Interconnection Between Calculus of Variations, Partial Differential Equations and Differential Geometry

open access: yesSelecciones Matemáticas
Calculus of variations is a fundamental mathematical discipline focused on optimizing functionals, which map sets of functions to real numbers. This field is essential for numerous applications, including the formulation and solution of partial ...
Delphin Mwinken
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calculus of variations and optimal control [PDF]

open access: yes, 1998
The theory of a Pontryagin minimum is developed for problems in the calculus of variations. The application of the notion of a Pontryagin minimum to the calculus of variations is a distinctive feature of this book.
Milyutin, A A, Osmolovskii, N P
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Optimizing Variational Problems through Weighted Fractional Derivatives

open access: yesFractal and Fractional
In this article, we explore a variety of problems within the domain of calculus of variations, specifically in the context of fractional calculus. The fractional derivative we consider incorporates the notion of weighted fractional derivatives along with
Ricardo Almeida
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Exploring Variational Methods in Hydro- and Hemodynamics Through Incompressible Velocity Distribution Sampling

open access: yesIEEE Access
Artificial neural networks are a robust tool for approximating spatial and temporal functions. This study introduces a novel method for hydro- and hemodynamics based on the minimization of a power loss.
Ivan Stebakov   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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