Results 131 to 140 of about 20,567 (306)
Some problems in the Calculus of Variations [PDF]
, 2017 We present some results and open problems in the Calculus of ...
Cellina, Arrigo
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Fractional Euler–Lagrange Equations Under Periodic and Antiperiodic Boundary Conditions
Fractal and FractionalIn this work, we derive necessary optimality conditions for a class of fractional variational problems involving Caputo-type derivatives. We consider functionals defined on appropriate spaces of absolutely continuous functions and study both periodic and
Ricardo Almeida
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Calculus of Variations [PDF]
, 2012 The Calculus of Variations is a highly applicable and advancing field. My thesis has only scraped the top of the applications and theoretical work that is possible within this branch of mathematics.
Whitney, Erin
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Determination of obstacles in Stokes flow by boundary measurement
Electronic Journal of Differential Equations, 2017 We study the determination of some obstacles in a Stokes flow domain with overdetermined boundary data. We use a method based on the topological sensitivity technique associated to the reciprocity gap function concept. We develop an asymptotic formula
Mohamed Abdelwahed +2 more
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FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
On the inequality of weierstrass for nonlocal functionals
Journal of Inequalities and Applications, 2001 The aim of this paper is to consider the problem of extremum of the nonlocal functional, which depends on a function and its derivative with respect to at several values of .
Kamenskii GA, Zabrodina Ju P
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