Results 61 to 70 of about 166,028,341 (301)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Calculus of variations: A differential form approach
We study integrals of the form integral(Omega) f(d omega(1), ..., d omega(m)), where m >= 1 is a given integer, 1 R is a continuous function. We introduce the appropriate notions of convexity, namely vectorial ext.
Sil, Swarnendu
core +1 more source
Existence and multiplicity results for homoclinic orbits of Hamiltonian systems
Homoclinic orbits play an important role in the study of qualitative behavior of dynamical systems. Such kinds of orbits have been studied since the time of Poincare.
Chao-Nien Chen, Shyuh-Yaur Tzeng
doaj
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Calculus of Variations and its Applications [PDF]
U ovome radu ukratko ćemo se upoznati sa osnovama varijacijskog računa. Bavit ćemo se problemom traženja lokalnog minimuma odredenog funkcionala na način da tražimo nužne i dovoljne uvjete postojanja ekstrema tog funkcionala.
Radojičić, Una
core
Periodic Solutions for a Class of 2n-Order Ordinary Differential Equations
Periodic solutions of high-order nonlinear differential equations are fundamental in dynamical systems, yet they remain challenging to establish with traditional methods.
Wenjin Li, Jiaxuan Sun, Yanni Pang
doaj +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The classical theory of calculus of variations for generalized functions
We present an extension of the classical theory of calculus of variations to generalized functions. The framework is the category of generalized smooth functions, which includes Schwartz distributions, while sharing many nonlinear properties with ...
Lecke Alexander +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

