Results 61 to 70 of about 1,630,900 (354)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
High-Precision Automatic Calibration Modeling of Point Light Source Tracking Systems
To realize high-precision and high-frequency unattended site calibration and detection of satellites, automatic direction adjustment must be implemented in mirror arrays.
Ruijin Li +6 more
doaj +1 more source
POLARIMETRIC CALIBRATION OF THE SPACEBORNE DIRECTIONAL POLARIMETRIC CAMERA INSTALLED ON THE GF-5 SATELLITE [PDF]
The Spaceborne Directional Polarimetric Camera (SDPC) is dedicated to obtain an accurate information of clouds and microphysical properties of aerosol particles via multi-angle, multi-spectral and multi-polarization observations. It images the Earth with
Y. Yuan +9 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Space temperature traceability based on near-site transfer of miniature fixed points
Long-term remote sensing precision depends on real-time radiation calibration, challenging the stability and accuracy of spaceborne calibrators in harsh space environments.
Ruiheng Sima +7 more
doaj +1 more source
More Accurate Pinhole Camera Calibration with Imperfect Planar Target
This paper presents a novel approach to camera calibration that improves final accuracy with respect to standard methods using precision planar targets, even if now inaccurate, unmeasured, roughly planar targets can be used.
Hirzinger, Gerd +3 more
core +1 more source
In the context of chemical metrology, calibration is the process of relating a known quantity of an analyte to the corresponding measured instrumental response through a mathematical relationship. Calibration permits the assignment of analyte levels in unknown samples based on the known levels of the ...
openaire +2 more sources
Functional magnetic resonance imaging with blood oxygenation level-dependent (BOLD) contrast has had a tremendous influence on human neuroscience in the last twenty years, providing a non-invasive means of mapping human brain function with often exquisite sensitivity and detail. However the BOLD method remains a largely qualitative approach.
openaire +2 more sources
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

