Results 81 to 90 of about 2,188,094 (296)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Hemodynamic monitoring: To calibrate or not to calibrate? Part 1 – Calibrated techniques [PDF]

open access: yesAnestezjologia Intensywna Terapia, 2015
Over recent decades, hemodynamic monitoring has evolved from basic cardiac output monitoring techniques to a broad variety of sophisticated monitoring devices with extra parameters. In order to reduce morbidity and mortality and optimize therapeutic strategies, different monitoring techniques can be used to guide fluid resuscitation and other medical ...
Peeters, Y.   +5 more
openaire   +4 more sources

Research And Experimental Verification of Absolute Measurement Facility Parameters for Radionuclide Neutron Source Emission Rate

open access: yesJournal of Isotopes
The manganese bath method is a commonly used method for determining neutron source emission rate.The Monte Carlo method (MCNP) was used to calculate the influence of main parameters such as bath radius,MnSO4 solution density,and measurement chamber ...
Haixian ZHANG   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Tracked Wall-Climbing Robot for Calibration of Large Vertical Metal Tanks

open access: yesApplied Sciences, 2019
Large vertical metal tanks are the primary vessels for the storage and turnover of crude oil, and the accuracy of their capacity calibrations are of great significance. The optical reference line method (ORLM) is used for capacity calibration and is time-
Xianlei Chen   +4 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Weather Radar Calibration Method Based on UAV-Suspended Metal Sphere

open access: yesSensors
Weather radar is an active remote sensing device used to monitor the full lifecycle changes in severe convective weather with high spatial and temporal resolution.
Fei Ye   +9 more
doaj   +1 more source

Conventional Calibration Versus EDF Calibration [PDF]

open access: yes
In this paper we analyze the impact of using alternative parameter calibration methodologies for general equilibrium models in the context of a particular application.
J. Felipe Córdova
core  

Abundance determination in HII regions from spectra without the [OII]3727+3729 line

open access: yes, 2010
We suggest an empirical calibration for determination of oxygen and nitrogen abundances and electron temperature in HII regions where the [OII]3727+3729 line (R_2) is not available.
Alloin   +37 more
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

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