Results 51 to 60 of about 44,442 (295)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pengaruh Penambahan Kapur Batu Pada Tanah Merah Terhadap Nilai California Bearing Ratio [PDF]

, 2019
Perkembangan peradaban manusia telah mengalami kemajuan yang sangat signifikan sejak seribu tahun terakhir, termasuk juga sektor transportasi. Kegiatan manusia didalam memenuhi kebutuhan hidupnya terkadang harus menyebabkan melakukan mobilisasi, oleh ...
Mendrofa, Sabar Tulus Parningotan
core  

Persamaan Nilai Korelasi Indeks Plastisitas (PI) Tanah Dengan California Bearing Ratio (CBR) Tanah Lempung Palangka Raya: Equation of Correlation Value of Soil Plasticity Index (PI) and California Bearing Ratio (CBR) of Palangka Raya Clay [PDF]

, 2019
During this time to get the value of California Bearing Ratio (CBR) planners will conduct field tests and/or laboratory tests. This takes time and is relatively large. For this reason, it is needed a practical matter or formulation about the relationship
Handayani, Noviyanthy, Saputra, Norseta Ajie   +1 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

An experimental study of the California bearing ratio of basalt fiber reinforced loess

Shuiwen dizhi gongcheng dizhi, 2021
In order to study the factors affecting the CBR value of the fiber-reinforced loess and the mechanism of the fiber-reinforced soil, chopped basalt fiber was used as the reinforcement material, and the CBR test was performed by changing the moisture ...
Peida LI, Yasheng LUO, Qingrui CHENG, Guogang WANG   +3 more
doaj   +1 more source

EFFECT OF WASTE MATERIALS ON CALIFORNIA BEARING RATIO FOR GRANULAR BASE

Journal of Engineering and Sustainable Development, 2021
It is known that paving is a system with multiple layers and the strength of each layer is reflected on the entire pavement. Two kinds of materials are used as the base layer, and the materials are divided into ordinary traditional granular materials and recycled materials such as foundry sand. This paper presents the results of laboratory tests in the
Jleel H. Rasheed, Zainab A. Alkaissi, Hanan A. Hassan   +2 more
openaire   +1 more source

Analisa Perhitungan Daya Dukung Tanah pada Lapisan Subgrade Jalan Menggunakan Metode California Bearing Ratio Lapangan [PDF]

, 2017
Jalan merupakan suatu sarana teknologi yang sangat membantu kehidupan manusia sehari-hari. Kegiatan manusia didalam memenuhi kebutuhan hidupnya tidak terlepas dari proses mobilisasi, sehingga kehidupan manusia tidak terlepas dari jalan.
Sihite, Warta Agustinus
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Utilization of Black Cotton Soil Stabilized with Brick Dust-Lime for Pavement Road Construction: An Experimental and Numerical Approach

The Baltic Journal of Road and Bridge Engineering, 2023
Black cotton soil is highly susceptible to volume change due to moisture fluctuations. This leads to the deformation of structures built on such soil. Therefore, the aim of this study is to improve the soil-bearing capacity and deformation analysis of ...
Damtew Melese, Belete Aymelo, Tewodros Weldesenbet, Alemineh Sorsa   +3 more
doaj   +1 more source