Results 61 to 70 of about 44,442 (295)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
California Bearing Ratio of Some Iraqi Dune Soils
Tikrit Journal of Engineering Sciences, 2015 This paper contains the results of CBR tests that performed on compacted samples of real dune sand (cohesionless sand grains) and pseudo dune sand which is a mixture of sand sized aggregate of clay and silt.
Yousif Al-Shakarchi +2 more
doaj
An assessment of how penetration curve adjustment affects the California bearing ratio (CBR)
Studia Geotechnica et Mechanica, 2021 With the rapidly developing road transport, there is a demand for new roads to be constructed and for the existing ones to be repaired or extended. The base of any road is its foundation, usually made of crushed or uncrushed aggregate.
Bednarek Łukasz
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
International Journal of Economic and Environment Geology, 2021 In this study, terrace soil investigation was carried out in project E-35 (phase-I) China-Pak Economic Corridor, Lesser Himalayas, North Pakistan. The methodology in current research is based on tests that include sieve analysis, plastic index, proctor ...
Salman Ahmed Khattak +5 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Determination of California bearing ratio values for different grounds and relations with ground properties [PDF]
, 2013 Fen Bilimleri Enstitüsü, Maden Mühendisliği Ana Bilim DalıBu çalışma kapsamında, yol kaplama tasarımında yaygın bir şekilde kullanılan Kaliforniya taşıma oranı deneyi (CBR) ile değişik zeminlerin CBR değerleri tespit edilmiştir. Daha sonra, bu zeminlerde
Çayir, Haci Mehmet
core
Pelatihan Uji Nilai California Bearing Ratio bagi Mahasiswa Teknik Sipil [PDF]
CBR (California Bearing Ratio) is a soil-bearing capacity test developed by the California State Highway Department. The principle of this test is penetration testing, which inserting an object into the sample.
Pamungkas, Wardana Galih +2 more
core +2 more sources
Effect of grain size distribution on california bearing ratio (CBR) and modified proctor parameters for granular materials [PDF]
, 2020 The California bearing ratio (CBR) and modified proctor parameters (maximum dry unit weight γd(max)γd(max) and optimum moisture content woptwopt) are valuable indicators of the compaction quality of subgrades, embankments and granular fills.
Fuentes, William +3 more
core +1 more source