Results 61 to 70 of about 293,270 (299)

Pengaruh Penambahan Air di Atas Kadar Air Optimum terhadap Nilai CBR dengan dan tanpa Rendaman pada Tanah Lempung yang Dicampur Abu Terbang [PDF]

, 2014
Clays are soft soil which have a low bearing capacity. One of the methods to determine the soil bearing capacity is CBR (California Bearing Ratio). Research on Laboratory for determining CBR value of soil generally performed on condition of optimum ...
', M. (Muhardi), Ningrum, P. '. (Puspa), Nugroho, S. A. (Soewignjo)   +2 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity. [PDF]

, 2018
Regulatory T cells (Tregs) are critical for maintaining immune homeostasis, but their presence in tumor tissues impairs anti-tumor immunity and portends poor prognoses in cancer patients.
Abnousian, Arbi, Bluestone, Jeffrey A, DuPage, Michel, Fong, Lawrence, Harwin, Tory, Mahuron, Kelly, Pagani, Massimiliano, Pai, Chien-Chun, Quiros, Jason, Ranzani, Valeria, Rosenblum, Michael D, Silveria, Stephanie, Van Gool, Frederic, Wang, David, Young, Arabella   +14 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

An assessment of how penetration curve adjustment affects the California bearing ratio (CBR)

Studia Geotechnica et Mechanica, 2021
With the rapidly developing road transport, there is a demand for new roads to be constructed and for the existing ones to be repaired or extended. The base of any road is its foundation, usually made of crushed or uncrushed aggregate.
Bednarek Łukasz
doaj   +1 more source

Forces on Centrifugal Pump Impellers [PDF]

, 1985
Forces are exerted on a centrifugal pump impeller, due to the asymmetry of the flow caused by the volute of diffuser, and to the motion of the center of the impeller whenever the shaft whirls. Recent work in the measurement of these forces as a function
Acosta, Allan, Brennen, Christopher E., Caughey, Thomas K., Jery, Belgacem   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

California Bearing Ratio (CBR) improvement of Kuantan clay subgrade by using high density polyethylene (HDPE) as stabilizer [PDF]

, 2012
Nowadays, the application of usmg high density polyethylene (HDPE) especially for storage and marketing of many liquids product are increased day by day.
Mohd Zulfadli, Juhari
core  

Herschel/HIFI observations of interstellar OH+ and H2O+ towards W49N: a probe of diffuse clouds with a small molecular fraction [PDF]

, 2010
We report the detection of absorption by interstellar hydroxyl cations and water cations, along the sight-line to the bright continuum source W49N.
A. Coutens, A. Cros, A. G. G. M. Tielens, A. Lorenzani, B. Godard, B. Mookerjea, Brogan, C. Gry, C. Joblin, C. Persson, C. Vastel, D. A. Neufeld, D. C. Lis, D. Teyssier, de Graauw, E. Dartois, E. Falgarone, E. Herbst, F. Boulanger, Fish, Gerin, Godard, Goicoechea, Gwinn, H. Gupta, Indriolo, J. Cernicharo, J. H. Black, J. Krełowski, J. Martín-Pintado, J. Pearson, J. R. Goicoechea, J. Stutzki, J. Zmuidzinas, K. Klein, K. M. Menten, Kre▯owski, L. A. Samoska, Le Petit, Le Petit, Liszt, M. De Luca, M. Gerin, M. Kazmierczak, M. Perault, M. Salez, M. Schmidt, Mürtz, Ossenkopf, P. Encrenaz, P. F. Goldsmith, P. Hennebelle, P. Hily-Blant, P. Rimmer, P. Sonnentrucker, Pilbratt, Plume, R. Kołos, R. Monje, R. Plume, R. Shipman, R. Szczerba, S. Philipp, S. Schlemmer, S. Yu, Sonnentrucker, Strahan, T. A. Bell, T. G. Phillips, T. Giesen, T. R. Geballe, Van der Werf, van Dishoeck, Vastel, Wehinger, Wyrowski   +75 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source