Results 111 to 120 of about 800,792 (268)

DMEK calling

Journal of Ophthalmic and Vision Research, 2016
Alfonso Vasquez Perez, Mehran Zarei-Ghanavati, Christopher Liu   +2 more
openaire   +3 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

First human fatality from H5N2 virus: Have we learnt lessons in pandemic preparedness?

New Microbes and New Infections
Faithful Miebaka Daniel, Victoria Ezinne Emeruwa, Lydia Daopuye   +2 more
doaj   +1 more source

Structure, personnel, and initiatives of antimicrobial stewardship programs in pediatric hospitals in the United States based on on-call participation: a cross-sectional survey. [PDF]

Antimicrob Steward Healthc Epidemiol
Alvira-Arill GR, Brace S, Morrisette T, Thacker S, Hamby A, Burgoon R, Gruss Z, Mills A, Lueking R, Mediwala Hornback K.   +9 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Signal brevity and compression in loud calls of the white-headed langur. [PDF]

iScience
Fan P, Liu Y, Zeng G, Liu R, Lawes MJ, Zhou Q, Li M.   +6 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Help-seeking and barriers to emergency care during out-of-hospital cardiac arrests in public housing areas: a qualitative study. [PDF]

BMJ Open
Juul Grabmayr A, Kragh AMR, Kjærholm S, Sheikh AP, Østergaard D, Hassager C, Folke F, Tjørnhøj-Thomsen T, Malta Hansen C.   +8 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Neurons in the bat auditory cortex encode class and complexity of future vocalizations. [PDF]

Commun Biol
Babl SS, Röhrig D, Hechavarría JC.
europepmc   +1 more source