Results 131 to 140 of about 5,999,398 (314)
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
An "intermountain miracle"? [PDF]
Idaho ; Utah ; Regional economics ; Economic conditions - West (U.S.)
Carolyn Sherwood-Call, Ronald H. Schmidt
core
EVALUASI DAN PENINGKATAN KUALITAS SISTEM PELAYANAN CALL CENTER DENGAN PENDEKATAN LEAN SIX SIGMA (Studi Kasus pada Call Center 147 PT. TELKOM DIVRE IV JATENG-DIY) [PDF]
, 2006 ABSTRAKSI PT. Telekomunikasi Indonesia, Tbk (PT. TELKOM) merupakan perusahaan telekomunikasi terbesar di Indonesia. Call center bertanggung jawab atas pertanyaan dan komplain pelanggan terhadap produk yang dikeluarkan PT. TELKOM.
LAILY, CHAIRIL
core
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Western manufacturing: bucking the national trend? [PDF]
Federal Reserve District, 12th ; West (U.S.)
Carolyn Sherwood-Call, Ronald H. Schmidt
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
MedienimpulseDie Tagung der Sektion „Allgemeine Erziehungswissenschaft“ der „Österreichischen Gesellschaft für Forschung und Entwicklung im Bildungswesen“ (ÖFEB) unter dem Titel „Pädagogisch-anthropologische Grenzziehungen: Menschenbilder in der Bildungswissenschaft“
Katharina Kaiser-Müller
doaj