Results 121 to 130 of about 5,999,398 (314)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Supertranslations call for superrotations [PDF]

open access: yes, 2010
We review recent results on symmetries of asymptotically flat spacetimes at null infinity. In higher dimensions, the symmetry algebra realizes the Poincar\'e algebra.
Barnich, Glenn, Troessaert, Cédric
core  

On Call [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2014
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

NAFTA and the western economy [PDF]

open access: yes
North American Free Trade Agreement ; International trade ; California ; Arizona ; Mexico ; West (U.S.)
Carolyn Sherwood-Call, Ronald H. Schmidt
core  

Teachers’ perceptions of lessons using computer assisted language learning [PDF]

open access: yes, 2010
The present study was designed to investigate the teachers’ perceptions of CALL lessons. The objectives of this study are to find out the problems faced by the teachers when conducting CALL lessons, to identify the perceptions teachers have on such ...
Malar Vasu, Sumitha, Mohd. Nor , Faizah
core  

Sequencing affective preparation before AI-mediated instruction: a quasi-experimental study of L2 writing outcomes and sustainability among multilingual undergraduate learners

open access: yesFrontiers in Education
This mixed-methods quasi-experimental study examined whether sequencing affective preparation before AI-supported instruction enhanced second language (L2) writing outcomes and promoted sustained learning among multilingual learners in an underserved ...
S. Sheeba Sisly   +2 more
doaj   +1 more source

Galois connecting call-by-value and call-by-name

open access: yesLogical Methods in Computer Science
We establish a general framework for reasoning about the relationship between call-by-value and call-by-name. In languages with computational effects, call-by-value and call-by-name executions of programs often have different, but related, observable behaviours.
Dylan McDermott, Alan Mycroft
openaire   +5 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Why do regional economies differ? [PDF]

open access: yes
Washington (State) ; Oregon ; Northwest, Pacific ; Regional economics ; Natural resources - West ; Federal Reserve District ...
Carolyn Sherwood-Call, Ronald H. Schmidt
core  

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