Results 241 to 250 of about 122,133 (302)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, Volume 20, Issue 7, Page 1780-1799, July 2026.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Spontaneous Helical Alignment of Smooth Muscle Cells to Form a Medial Layer for Engineered Microvasculature

Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.
Spontaneous helical alignment of smooth muscle cells is induced within resistance‐vessel‐sized channels patterned within a hydrogel. The extent of the cells’ orientation angle is dependent on the presence and composition of ECM proteins lining the channel wall and cell seeding density.
Victoria D. Vest, Katherine J. Young, Isabella K. Holtz, Mark Mc Veigh, James D. West, Leon M. Bellan   +5 more
wiley   +1 more source

Suppression of Calcium Influx Reduces Coxsackievirus B3 Lethality With Elevated Interferon Beta Responses in Mice. [PDF]

J Med Virol
Hsiao YL, Hung CH, Yeh MT, Chen SH.
europepmc   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Long-term follow-up of patients with catecholaminergic polymorphic ventricular tachycardia related to a novel <i>CALM2</i> variant. [PDF]

J Cardiol Cases
Ohno S, Kato K, Fukuyama M, Hirono K, Nishida K, Horie M.   +5 more
europepmc   +1 more source

Commentary on: direct binding of calmodulin to the cytosolic C-terminal regions of sweet/umami taste receptors. [PDF]

J Biochem
Misaka T.
europepmc   +1 more source

Glycine-GLRA1-calmodulin signaling regulates endoplasmic reticulum calcium to sustain insulin secretion and β-cell function. [PDF]

Life Metab
Zhang J, Cao Z, Yang J, Zhu K, Liu S, Liu W, Lu J, Zhao H, Dai W, Chang C, Ye H, Du X, Wang Q, Jiang B, Wang S, Jin L, Zhao T, Li P, Vidal-Puig A, Zheng Y, Shi L, Huang L.   +21 more
europepmc   +1 more source

Structural and functional insights into calmodulin-mediated lipid binding and proteolytic cleavage of the M-PMV matrix protein. [PDF]

J Biol Chem
Buresova K, Nesporova T, Prchal J, Banerjee S, Castoralova M, Hodbodova L, Kukacka Z, Junkova P, Ruml T.   +8 more
europepmc   +1 more source

Animal models for diabetic kidney disease: perspectives and prospects. [PDF]

Front Vet Sci
Zeng M, Gong Q, Shen H, Chen L, Zhang W.
europepmc   +1 more source