Results 1 to 10 of about 76,625 (109)
Microchip Electrophoresis Assay for Calmodulin Binding Proteins. [PDF]
J Sep Sci, 2021 AbstractThe calcium signaling protein calmodulin regulates numerous intracellular processes. We introduce a sensitive microchip assay to separate and detect calmodulin binding proteins. The assay utilizes an optimized microchip electrophoresis protein separation platform with laser‐induced fluorescence detection.
Samarasinghe TN, Zeng Y, Johnson CK.
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Calmodulin Binding Proteins and Alzheimer's Disease. [PDF]
J Alzheimers Dis, 2015 Abstract The small, calcium-sensor protein, calmodulin, is ubiquitously expressed and central to cell function in all cell types. Here the literature linking calmodulin to Alzheimer’s disease is reviewed. Several experimentally-verified calmodulin-binding proteins are involved in the formation of amyloid-β plaques including amyloid-β protein precursor,
O'Day DH, Eshak K, Myre MA.
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Pull-down of calmodulin-binding proteins. [PDF]
J Vis Exp, 2012 Calcium (Ca(2+)) is an ion vital in regulating cellular function through a variety of mechanisms. Much of Ca(2+) signaling is mediated through the calcium-binding protein known as calmodulin (CaM). CaM is involved at multiple levels in almost all cellular processes, including apoptosis, metabolism, smooth muscle contraction, synaptic plasticity, nerve ...
Kaleka KS +3 more
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Structural Aspects and Prediction of Calmodulin-Binding Proteins. [PDF]
Int J Mol Sci, 2020 Calmodulin (CaM) is an important intracellular protein that binds Ca2+ and functions as a critical second messenger involved in numerous biological activities through extensive interactions with proteins and peptides. CaM’s ability to adapt to binding targets with different structures is related to the flexible central helix separating the N- and C ...
Andrews C, Xu Y, Kirberger M, Yang JJ.
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Calmodulin binding proteins and neuroinflammation in multiple neurodegenerative diseases. [PDF]
BMC Neurosci, 2022 AbstractCalcium dysregulation (“Calcium Hypothesis”) is an early and critical event in Alzheimer’s and other neurodegenerative diseases. Calcium binds to and regulates the small regulatory protein calmodulin that in turn binds to and regulates several hundred calmodulin binding proteins.
O'Day DH, Huber RJ.
europepmc +6 more sources
Calmodulin and Calmodulin Binding Proteins in Dictyostelium: A Primer. [PDF]
Int J Mol Sci, 2020 Dictyostelium discoideum is gaining increasing attention as a model organism for the study of calcium binding and calmodulin function in basic biological events as well as human diseases. After a short overview of calcium-binding proteins, the structure of Dictyostelium calmodulin and the conformational changes effected by calcium ion binding to its ...
O'Day DH, Taylor RJ, Myre MA.
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Calmodulin Binding Proteins and Alzheimer’s Disease: Biomarkers, Regulatory Enzymes and Receptors That Are Regulated by Calmodulin [PDF]
International Journal of Molecular Sciences, 2020 Danton H O'Day, O'Day Danton H
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Calmodulin-binding proteins in bovine semen [PDF]
Reproduction, 1993 An 125I-labelled calmodulin gel overlay procedure was used to direct calmodulin-binding proteins in bovine spermatozoa and seminal plasma. Several calmodulin-binding proteins with molecular masses ranging from 12 to > 200 kDa were detected in epididymal and ejaculated spermatozoa.
P, Manjunath +3 more
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Phosphofructokinase is a calmodulin binding protein
FEBS Letters, 1983 A trial to purify myosin light chain kinase from crude myosin led to the isolation of a M r 85 000 calmodulin binding protein different from this enzyme. Because it showed inherent phosphofructokinase activity we investigated its relation to this enzyme.
Mayr, Georg W., Heilmeyer, Ludwig M.G.
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Cardiac sarcoplasmic-reticulum calmodulin-binding proteins. Modulation of calmodulin binding to phospholamban by phosphorylation [PDF]
Biochemical Journal, 1985 The gel-overlay technique with 125I-labelled calmodulin allowed the detection of several calmodulin-binding proteins of Mr 280 000, 150 000, 97 000, 56 000, 35 000 and 24 000 in canine cardiac sarcoplasmic reticulum. Only two calmodulin-binding proteins could be identified unambiguously.
A, Molla, J P, Capony, J G, Demaille
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