Calmodulin Binding Proteins and Alzheimer’s Disease: Biomarkers, Regulatory Enzymes and Receptors That Are Regulated by Calmodulin [PDF]
International Journal of Molecular Sciences, 2020 Danton O'Day, O'Day Danton H
exaly +2 more sources
Calmodulin Binding Domains in Critical Risk Proteins Involved in Neurodegeneration
Current Issues in Molecular Biology, 2022 Neurodegeneration leads to multiple early changes in cognitive, emotional, and social behaviours and ultimately progresses to dementia. The dysregulation of calcium is one of the earliest potentially initiating events in the development of ...
Danton H. O’Day
doaj +1 more source
The Role of Calmodulin vs. Synaptotagmin in Exocytosis
Frontiers in Molecular Neuroscience, 2021 Exocytosis is a Ca2+-regulated process that requires the participation of Ca2+ sensors. In the 1980s, two classes of Ca2+-binding proteins were proposed as putative Ca2+ sensors: EF-hand protein calmodulin, and the C2 domain protein synaptotagmin. In the
Renhao Xue +8 more
doaj +1 more source
Calmodulin-binding proteins in bovine semen [PDF]
Reproduction, 1993 An 125I-labelled calmodulin gel overlay procedure was used to direct calmodulin-binding proteins in bovine spermatozoa and seminal plasma. Several calmodulin-binding proteins with molecular masses ranging from 12 to > 200 kDa were detected in epididymal and ejaculated spermatozoa.
P, Manjunath +3 more
openaire +2 more sources
Next generation calmodulin affinity purification: Clickable calmodulin facilitates improved protein purification. [PDF]
PLoS ONE, 2018 As the proteomics field continues to expand, scientists are looking to integrate cross-disciplinary tools for studying protein structure, function, and interactions. Protein purification remains a key tool for many characterization studies.
Julia G Fraseur, Tamara L Kinzer-Ursem
doaj +1 more source
Calmodulin-Binding Protein Detection Using a Non-Radiolabeled Calmodulin Fusion Protein
BioTechniques, 2001 Calmodulin-binding proteins are involved in numerous cellular signaling pathways. The biotinylated-calmodulin overlay is a nonradioactive method widely used to detect calmodulin-binding proteins in tissue and cell samples.
Gloria Murray +3 more
doaj +1 more source
Phosphofructokinase is a calmodulin binding protein
FEBS Letters, 1983 A trial to purify myosin light chain kinase from crude myosin led to the isolation of a M r 85 000 calmodulin binding protein different from this enzyme. Because it showed inherent phosphofructokinase activity we investigated its relation to this enzyme.
Mayr, Georg W., Heilmeyer, Ludwig M.G.
openaire +2 more sources
BioTechniques, 1996 To identify calmodulin-binding proteins in cellular extracts and tissue homogenates and to analyze purified calmodulin target proteins, overlay procedures using 125I-calmodulin or, more recently, nonradioactive biotinylated calmodulin have been widely ...
Roland Fischer, Yu Wei, Martin Berchtold
doaj +1 more source
HALOTHANE MEDIATED INHIBITION OF CALMODULIN-NEUROPEPTIDE BINDING
Zagazig Journal of Pharmaceutical Sciences, 1996 Binding of volatile anesthetics by proteins has been proposed as a mechanism of anesthesia. There is no evidence, however, that anesthetics at clinically relevant concentrations can interact directly with lipid - free preparations of receptors or signal ...
Mohamed Adel El-Sayed +2 more
doaj +1 more source
Cardiac sarcoplasmic-reticulum calmodulin-binding proteins. Modulation of calmodulin binding to phospholamban by phosphorylation [PDF]
Biochemical Journal, 1985 The gel-overlay technique with 125I-labelled calmodulin allowed the detection of several calmodulin-binding proteins of Mr 280 000, 150 000, 97 000, 56 000, 35 000 and 24 000 in canine cardiac sarcoplasmic reticulum. Only two calmodulin-binding proteins could be identified unambiguously.
A, Molla, J P, Capony, J G, Demaille
openaire +2 more sources