Results 51 to 60 of about 844,015 (339)

Chronic Caloric Restriction and Exercise Improve Metabolic Conditions of Dietary-Induced Obese Mice in Autophagy Correlated Manner without Involving AMPK

open access: yesJournal of Diabetes Research, 2013
Aim. To investigate the role of AMPK activation and autophagy in mediating the beneficial effects of exercise and caloric restriction in obesity. Methods.
Mingxia Cui   +4 more
doaj   +1 more source

Effects of maternal nutrient restriction during the periconceptional period on placental development in the mouse.

open access: yesPLoS ONE, 2021
Maternal undernutrition has detrimental effects on fetal development and adult health. Total caloric restriction during early pregnancy followed by adequate nutrition for the remainder of gestation, is particularly linked to cardiovascular and metabolic ...
Gerialisa Van Gronigen Case   +3 more
doaj   +1 more source

Resveratrol and caloric restriction prevent hepatic steatosis by regulating SIRT1-autophagy pathway and alleviating endoplasmic reticulum stress in high-fat diet-fed rats. [PDF]

open access: yesPLoS ONE, 2017
Studies have demonstrated that resveratrol (a natural polyphenol) and caloric restriction activate Sirtuin-1 (SIRT1) and induce autophagy. Furthermore, autophagy is induced by the SIRT1-FoxO signaling pathway and was recently shown to be a critical ...
Shibin Ding   +5 more
doaj   +1 more source

Effects of ketogenic diet containing medium-chain fatty acids on serum inflammatory factor and mTOR signaling pathway in rats

open access: yesChemical and Biological Technologies in Agriculture, 2020
Background The ketogenic diet (KD) can promote the anti-inflammatory metabolic state and increase ketone body level in rats. This study was to explore the effects and differences of KD with or without medium-chain fatty acids (MCFAs) on serum ...
Huan Liu   +5 more
doaj   +1 more source

NOT JUST CALORIC RESTRICTION: A COMPLEX APPROACH TO PROLONG LIFESPAN AND IMPROVE QUALITY OF LIFE

open access: yesCentral Asian Journal of Medical Hypotheses and Ethics, 2021
Aging is an urgent healthcare issue in view of the rapid growth of the proportion of older persons. Searching for reliable aging biomarkers and prolonging lifespan are increasingly important scientific directions.
Galina V. Morgunova
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The comparative effect of fasting with and without caloric restriction in Rat on oxidative stress parameters [PDF]

open access: yesJournal of Fasting and Health, 2016
Introduction: Fasting, like Islamic Ramadan Fasting, has been associated with health benefits. Islamic Ramadan fasting, a form of caloric restriction (CR) or alternate day fasting that.
Nurina Tyagita   +2 more
doaj   +1 more source

Caloric restriction, caloric restriction mimetics, and healthy aging in Okinawa [PDF]

open access: yesCurrent Opinion in Clinical Nutrition and Metabolic Care, 2013
To examine the role of two nutritional factors implicated in the healthy aging of the Okinawans: caloric restriction; and traditional foods with potential caloric restriction-mimetic properties.Caloric restriction is a research priority for the US National Institute on Aging. However, little is known regarding health effects in humans.
Bradley J, Willcox, Donald C, Willcox
openaire   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The effect of 8 weeks caloric restriction on PLIN5 and ATGL visceral adipose tissue and insulin resistance in type 2 diabetic male rats

open access: yesFiyz̤, 2022
Background: There is a close link between eating fatty foods, the prevalence of obesity and type 2 diabetes. This study aimed to evaluation the effect of 8 weeks caloric restriction on Perilipins (PLIN5) and ATGL visceral adipose tissue and insulin ...
Arash Alimoradi   +2 more
doaj  

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