Results 161 to 170 of about 384,773 (212)

Semaglutide in type 2 diabetes and chronic kidney disease in Australia: practical clinical considerations from a multidisciplinary panel

Internal Medicine Journal, EarlyView.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major causes of morbidity and mortality in people with type 2 diabetes (T2D). Contemporary CKD guidelines increasingly support incorporation of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) as an additional pillar of cardiorenal therapy alongside renin–angiotensin ...
Eugenia Pedagogos, Roger Chen, Adam Nelson, Sunil Badve, Roy Rasalam, Richard MacIsaac   +5 more
wiley   +1 more source

SIRT1 Activators as Geroprotective Agents in Brain Aging: Mechanisms and Therapeutic Potential. [PDF]

Neuromolecular Med
Alameen AAM, Al-Kuraishy HM, Al-Gareeb AI, Alexiou A, Papadakis M, Faheem SA, El-Saber Batiha G.   +6 more
europepmc   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

How Gut Microbiota Influence Healthy Aging: Overview of Reviews. [PDF]

Geriatrics (Basel)
Todmal TG, Bibi R, Cangelosi G, Panella M, Masini A.   +4 more
europepmc   +1 more source

Conditions and timing for the precipitation of early marine diagenetic dolomite in the Triassic Dolomia Principale (northern Italy)

Sedimentology, EarlyView.
ABSTRACT Thermodynamic constraints and empirical evidence often suggest that fabric‐retentive replacement dolomites are stable carbonate minerals that preserve ancient seawater properties. This study evaluates this hypothesis by examining the Upper Triassic Dolomia Principale in Northern Italy.
Vivien Folliot, Giovanna Della Porta, Mathias Mueller, Fabrizio Berra, Benjamin F. Walter, Aratz Beranoaguirre, Sylvia Riechelmann, Oskar Schramm, Adrian Immenhauser   +8 more
wiley   +1 more source

Effects of anti-aging diets and exercise on age-related musculoskeletal diseases via gut microbiota modulation. [PDF]

Ann Med
Yu M, Guo P, Liu Q, Zhang XA.
europepmc   +1 more source

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

Experimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee, Tessa R. Flood, Sophie L. Russell, James J. McCormick, Kelli E. King, Naoto Fujii, Tatsuro Amano, Sean Notley, Glen P. Kenny   +8 more
wiley   +1 more source

Why Do We Lose Bone During Weight Loss: Can It Be Prevented? [PDF]

Curr Osteoporos Rep
Shapses SA, McGuire BD.
europepmc   +1 more source

Heat treatment combined with hybrid exercises retraining mitigates cellular markers of protein turnover after hindlimb suspension in male mice: A pilot study

Experimental Physiology, EarlyView.
Abstract Recent evidence suggests that heat treatment (HT) and resistance training can limit skeletal muscle mass loss during immobilization. However, the effects of repeated HT sessions combined with hybrid exercises (EX), which promote both endurance and resistance responses, on muscle protein turnover following hindlimb unloading (HU) remain ...
Tom Normand‐Gravier, Robert Solsona, Christelle Bertrand‐Gaday, Margot Issertine, Florence Sabatier, Flavie Arnould, Sébastien Racinais, Fabio Borrani, Henri Bernardi, Anthony M. J. Sanchez   +9 more
wiley   +1 more source