Results 31 to 40 of about 5,986,901 (283)

Anomalous (Exergonic) Behavior in the Transfer of Electrons between Donors and Acceptors: Mobility, Energy, Caloric Capacity, and Entropy

open access: yesACS Omega, 2022
Understanding the kinetics of electron transfer reactions involves active research in physics, chemistry, biology, and nano-tech. Here, we propose a model to apply in a broader framework by establishing a connection between thermodynamics and kinetics ...
A. M. Cabanas   +3 more
semanticscholar   +1 more source

The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study. [PDF]

open access: yesPLoS ONE, 2014
Synaptic loss is a major hallmark of Alzheimer's disease (AD). Disturbed organisation of large-scale functional brain networks in AD might reflect synaptic loss and disrupted neuronal communication.
Hanneke de Waal   +7 more
doaj   +1 more source

Homeostasis balance, homeostasis imbalance or distinct motivational processes? Comments on Marks (2015) ‘Homeostatic Theory of Obesity’

open access: yesHealth Psychology Open, 2016
In his article, ‘Homeostatic theory of obesity’, Marks suggested that imbalances in homeostatic processes could explain weight gain and obesity. He proposes that over-consumption of high-caloric, low-nutrient and low satiating foods, combined with a ...
Luc G Pelletier   +3 more
doaj   +1 more source

Head circumference as an epigenetic risk factor for maternal nutrition

open access: yesFrontiers in Nutrition, 2022
Nutrition indicators for malnutrition can be screened by many signs such as stunting, underweight or obesity, muscle wasting, and low caloric and nutrients intake. Those deficiencies are also associated with low socioeconomic status.
Maria J. Miele   +15 more
doaj   +1 more source

Relations of change in fruit and vegetable intake with overall energy reduction and physical activity with weight change: Assessing theory-based psychosocial mediators

open access: yesJournal of Sport and Health Science, 2019
Background: Increased physical activity and fruit and vegetable (FV) intake are typically suggested to counter obesity. Sustained behavior change in those areas has, however, been poor, possibly because of a lack of understanding of the effects of ...
James J. Annesi
doaj   +1 more source

Game-theoretical description of the go-or-grow dichotomy in tumor development for various settings and parameter constellations

open access: yesScientific Reports, 2023
A medically important feature of several types of tumors is their ability to “decide” between staying at a primary site in the body or leaving it and forming metastases. The present theoretical study aims to provide a better understanding of the ultimate
Shalu Dwivedi   +4 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Understanding the Multifaceted Process of Aging: Theories, Mechanisms, and Implications for Treatment

open access: yesAl-SalamJournal for Medical Science
The aging process is a multifaceted biological phenomenon characterized by alterations at the molecular, cellular, and organ levels that culminate in a gradual, unavoidable, and unavoidable reduction in the body's capacity to react suitably to internal ...
Omar M. Ameen, Ghada A. Taqa
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Impaired maturation of resting-state connectivity in anorexia nervosa from adolescence to adulthood: differential mechanisms of consummatory vs. anticipatory responses through a symptom provocation paradigm

open access: yesFrontiers in Behavioral Neuroscience
This functional magnetic resonance imaging (fMRI) study examined resting-state (RS) connectivity in adolescent and adult patients with anorexia nervosa (AN) using symptom provocation paradigms.
Andrea Mendez-Torrijos   +13 more
doaj   +1 more source

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