Results 41 to 50 of about 239 (208)
Journal of Obesity, 2010 Background. Psychological factors' effect on weight loss is poorly understood, in general, and specifically in the severely obese. Objective. To examine whether a behavioral model based on tenets of social cognitive and self-efficacy theory will increase
James J. Annesi, Srinivasa Gorjala
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Thermal dileptons as fireball thermometer and chronometer
Physics Letters B, 2016 Thermal dilepton radiation from the hot fireballs created in high-energy heavy-ion collisions provides unique insights into the properties of the produced medium.
Ralf Rapp, Hendrik van Hees
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
OPTIMIZATION OF THE RECIPE OF MULTICOMPONENT FOODS WITH METHODS OF SIMILARITY THEORY AND WAYS OF ITS PRACTICAL IMPLEMENTATION [PDF]
Техника и технология пищевых производств, 2015 The article presents the results of the development of technology of instant soup preparation, making it possible to correct the energy value of food quickly without changing the volume of portions, the original component composition and organoleptic ...
Nugmanov A.H. +3 more
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The metabolic underpinnings of temperature-dependent predation in a key marine predator
Frontiers in Marine Science, 2023 IntroductionChanges in temperature can fundamentally transform how species interact, causing wholesale shifts in ecosystem dynamics and stability. Yet we still have a limited understanding of how temperature-dependence in physiology drives temperature ...
Samantha R. Csik +8 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Appell Transformation and Canonical Transforms
Symmetry, Integrability and Geometry: Methods and Applications, 2011 The interpretation of the optical Appell transformation, as previously elaborated in relation to the free-space paraxial propagation under both a rectangular and a circular cylindrical symmetry, is reviewed.
Amalia Torre
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FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source