Results 41 to 50 of about 5,430,372 (258)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Oxi-Inflamm-Aging: a New Theory with Practical Implications
Oxidative stress causes an impairment of the physiological systems essential for maintaining homeostasis, including the immune system. Immune dysregulation leads to a chronic low-grade inflammatory state in aging. This is the basis of the new integrative
Ángel Julio Romero Cabrera +1 more
doaj +2 more sources
In the beginning of the 19th Century, there were two theories absolutely different on the nature of the heat: the Mechanical Theory of the Heat and the Caloric Theory.
Antônio Bráz de Pádua +2 more
doaj
This paper aimed to carry out an analysis of Joule’s original texts, written in the middle of the XIX century, trying to understand how the changes in heat concept occurred throughout his work. To support the theoretical analysis, a literature review was
Bianca Cintra de Carvalho +1 more
doaj +1 more source
Energy balance and cancers [PDF]
Energy balance results from the exact equilibrium between caloric intake and caloric expenditure. A caloric intake larger than caloric expenditure results in overweight, even obesity, but other determinants, like hormonal dysfunction and/or genetic ...
Gerber, Mariette, Corpet, Denis E.
core
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Sex ratio theory suggests that females should bias offspring sex ratios based on maternal condition and the availability of critical food resources. Work in birds indicates that females do, indeed, bias sex ratios according to maternal condition and food
James Curry +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
OPTIMIZATION OF THE RECIPE OF MULTICOMPONENT FOODS WITH METHODS OF SIMILARITY THEORY AND WAYS OF ITS PRACTICAL IMPLEMENTATION [PDF]
The article presents the results of the development of technology of instant soup preparation, making it possible to correct the energy value of food quickly without changing the volume of portions, the original component composition and organoleptic ...
Nugmanov A.H. +3 more
doaj
Background. Psychological factors' effect on weight loss is poorly understood, in general, and specifically in the severely obese. Objective. To examine whether a behavioral model based on tenets of social cognitive and self-efficacy theory will increase
James J. Annesi, Srinivasa Gorjala
doaj +1 more source

