Results 61 to 70 of about 5,430,372 (258)
, 2022 Cooling systems based on the caloric effects of ferroic materials show high potential for various cooling and heat-pumping applications due to their potentially high efficiencies and the lack of any environmentally hazardous refrigerants.
Kalizan, Jan, Tušek, Jaka
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Smartloss: A Personalized Mobile Health Intervention for Weight Management and Health Promotion
JMIR mHealth and uHealth, 2016 BackgroundSynonymous with increased use of mobile phones has been the development of mobile health (mHealth) technology for improving health, including weight management.
Martin, Corby K +5 more
doaj +1 more source
Celebrating Haldane's `Luttinger liquid theory' [PDF]
, 2017 This short piece celebrates Haldane's seminal J. Phys. C 14, 2585 (1981) paper laying the foundations of the modern theory of Luttinger liquids in one-dimensional ...
Sub Cond-Matter Theory, Stat & Comp Phys +7 more
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
PLoS ONE, 2023 Unhealthy food advertisements ("advertisements" hereafter referred to as "ads") are linked to poor diet and obesity, and food companies disproportionally target Black youth. Little is known about the mechanisms whereby food ads influence diet.
Omni Cassidy +8 more
doaj +1 more source
Mechanisms of Caloric Stimulation of the Pigeon's Vestibular System
, 1991 Bárány's thermal convection theory was questioned after the observation of caloric nystagmus in space under microgravity conditions. Our study was undertaken to gain more insight into the mechanisms that play a role during caloric stimulation of the ...
Wit, H.P +6 more
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source