Enlightening brain energy metabolism
Neurobiology of Disease, 2023 Brain tissue metabolism is distributed across several cell types and subcellular compartments, which activate at different times and with different temporal patterns.
L.F. Barros +3 more
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Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 [PDF]
Frontiers in Neurology, 2021 Alzheimer's disease (AD) is currently one of the main diseases afflicting the elderly in the world. In recent years, more and more studies have shown that brain energy metabolism disorders are the key pathogenic factors and main early pathological ...
Yi-Hong Du +8 more
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Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives [PDF]
Frontiers in Physiology, 2022 Astrocytes play key roles in the regulation of brain energy metabolism, which has a major impact on brain functions, including memory, neuroprotection, resistance to oxidative stress and homeostatic tone.
Elidie Beard +4 more
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Elucidating reaction dynamics in a model of human brain energy metabolism. [PDF]
PLoS Computational BiologyEnergy metabolism is essential to brain function and Bioinformatics, but its study is experimentally challenging. Similarly, biologically accurate computational models are too complex for simple investigations.
Dimitrios G Patsatzis +4 more
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Brain Regulation of Energy Metabolism [PDF]
Endocrinology and Metabolism, 2016 In healthy individuals, energy intake is in balance with energy expenditure, which helps to maintain a normal body weight. The brain's inability to control energy homeostasis underlies the pathology of hyperphagia and obesity.
Eun Roh, Min-Seon Kim
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Neuroglia and brain energy metabolism. [PDF]
Handb Clin NeurolThe glial control of energy homeostasis is of crucial importance for health and disease. Astrocytes in particular play a major role in controlling the equilibrium among adenosine 5'-triphosphate (ATP), adenosine 5'-diphosphate (ADP), adenosine 5'-monophosphate (AMP), and adenosine. Any energy crisis leads to a drop in ATP, and the resulting increase in
Peter-Okaka U, Boison D.
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Pathology and Treatments of Alzheimer’s Disease Based on Considering Changes in Brain Energy Metabolism Due to Type 2 Diabetes [PDF]
MoleculesAlzheimer’s disease (AD) is a progressive neurodegenerative disorder with cognitive dysfunction, memory decline, and behavioral disturbance, and it is pathologically characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the ...
Hidekatsu Yanai +3 more
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Brain Energy Metabolism in Two States of Mind Measured by Phosphorous Magnetic Resonance Spectroscopy [PDF]
Frontiers in Human Neuroscience, 2021 Introduction: Various functional neuroimaging studies help to better understand the changes in brain activity during meditation. The purpose of this study was to investigate how brain energy metabolism changes during focused attention meditation (FAM ...
Malik Galijašević +14 more
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Energy Metabolism Decline in the Aging Brain—Pathogenesis of Neurodegenerative Disorders
Metabolites, 2020 There is a growing body of evidencethat indicates that the aging of the brain results from the decline of energy metabolism. In particular, the neuronal metabolism of glucose declines steadily, resulting in a growing deficit of adenosine triphosphate ...
Janusz Wiesław Błaszczyk
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GSK3β Regulates Brain Energy Metabolism. [PDF]
Cell Rep, 2018 GSK3β is a serine threonine kinase implicated in the progression of Alzheimer's disease. Although the role of GSK3β in growth and pathology has been extensively studied, little is known about the metabolic consequences of GSK3β manipulation, particularly in the brain.
Martin SA +8 more
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