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Enlightening brain energy metabolism
Neurobiology of Disease, 2023 Brain tissue metabolism is distributed across several cell types and subcellular compartments, which activate at different times and with different temporal patterns.
L.F. Barros +3 more
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Brain Regulation of Energy Metabolism [PDF]
Endocrinology and Metabolism, 2016 In healthy individuals, energy intake is in balance with energy expenditure, which helps to maintain a normal body weight. The brain's inability to control energy homeostasis underlies the pathology of hyperphagia and obesity.
Eun Roh, Min-Seon Kim
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Energy metabolism in childhood neurodevelopmental disorders
EBioMedicine, 2021 Whereas energy function in the aging brain and their related neurodegenerative diseases has been explored in some detail, there is limited knowledge about molecular mechanisms and brain networks of energy metabolism during infancy and childhood.
Oyarzábal A +3 more
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Frontiers in Neurology, 2021 Alzheimer's disease (AD) is currently one of the main diseases afflicting the elderly in the world. In recent years, more and more studies have shown that brain energy metabolism disorders are the key pathogenic factors and main early pathological ...
Yi-Hong Du +8 more
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Cerebral metabolic mechanisms of migraine
Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Migraine is one of the most common primary headaches, but its pathogenesis remains unclear. Recent studies have found that the onset of migraine may be a response to the imbalance of brain energy metabolism and oxidative stress, suggesting that migraine ...
JIN Hai⁃di +3 more
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Maintenance of mitochondrial homeostasis for Alzheimer's disease: Strategies and challenges
Redox Biology, 2023 Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, and its early onset is closely related to mitochondrial energy metabolism. The brain is only 2% of body weight, but consumes 20% of total energy needs.
Ying Han +6 more
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Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans
Frontiers in Aging Neuroscience, 2020 The brain requires a large amount of energy, mostly derived from the metabolism of glucose, which decreases substantially with age and neurological diseases.
Bernard Cuenoud +6 more
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BBA Advances, 2023 The brain is an organ that consumes a lot of energy. In the brain, energy is required for synaptic transmission, numerous biosynthetic processes and axonal transport in neurons, and for many supportive functions of glial cells.
Maria M. Bayliak +2 more
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Neural regulation of energy and bone homeostasis by the synaptic adhesion molecule Calsyntenin-3
Experimental and Molecular Medicine, 2020 Bone metabolism: Regulation by brain protein A protein that is highly expressed in brain cells plays a vital role in maintaining balanced energy expenditure and bone health.
Sung-Jin Kim +11 more
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Cell Reports, 2023 Summary: Neutrophil aggregation and clearance are important factors affecting neuroinflammatory injury during acute ischemic stroke. Emerging evidence suggests that energy metabolism is essential for microglial functions, especially microglial ...
Lei Li +9 more
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