Results 11 to 20 of about 2,320 (212)
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation [PDF]
Cell Metabolism, 2011 The energy requirements of the brain are very high, and tight regulatory mechanisms operate to ensure adequate spatial and temporal delivery of energy substrates in register with neuronal activity. Astrocytes-a type of glial cell-have emerged as active players in brain energy delivery, production, utilization, and storage.
Belanger M, Allaman I, Magistretti PJ
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GSK3β Regulates Brain Energy Metabolism [PDF]
Cell Reports, 2018 GSK3β is a serine threonine kinase implicated in the progression of Alzheimer's disease. Although the role of GSK3β in growth and pathology has been extensively studied, little is known about the metabolic consequences of GSK3β manipulation, particularly in the brain.
Martin, Stephen A. +8 more
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Impairments in Oxidative Glucose Metabolism in Epilepsy and Metabolic Treatments Thereof
Frontiers in Cellular Neuroscience, 2018 There is mounting evidence that oxidative glucose metabolism is impaired in epilepsy and recent work has further characterized the metabolic mechanisms involved.
Tanya McDonald +3 more
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Scientific Reports, 2022 Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as short chain fatty acids (SCFAs). SCFAs have been proposed as a possible mechanism through which the gut
Tiffany A. Fillier +8 more
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Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives
Frontiers in Physiology, 2022 Astrocytes play key roles in the regulation of brain energy metabolism, which has a major impact on brain functions, including memory, neuroprotection, resistance to oxidative stress and homeostatic tone.
Elidie Beard +4 more
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Impairments in Brain Bioenergetics in Aging and Tau Pathology: A Chicken and Egg Situation?
Cells, 2021 The brain is the most energy-consuming organ of the body and impairments in brain energy metabolism will affect neuronal functionality and viability. Brain aging is marked by defects in energetic metabolism.
Amandine Grimm
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Brain energy metabolism in streptozotocin-diabetes [PDF]
Biochemical Journal, 1988 Regional brain glucose use was measured in rats with streptozotocin-induced diabetes (65 mg/kg intravenously) of 1 or 4 weeks duration, by using [6-14C]glucose and quantitative autoradiography. The concentrations of several metabolites were measured in plasma and brain. Results were compared with those from normal untreated rats. Glucose concentrations
A M, Mans +3 more
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Metabolisme Energi pada Cedera Otak Traumatik
Jurnal Neuroanestesi Indonesia, 2012 Cedera otak traumatik mengakibatkan terjadinya kaskade gangguan fisiologi dan biokimia yang berpengaruh pada metabolisme dan produksi energi serebral. Setelah cedera otak traumatik, terjadi perubahan berkelanjutan pada metabolisme energi serebral yang ...
I Putu Pramana Suarjaya +2 more
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Current technical approaches to brain energy metabolism [PDF]
Glia, 2017 AbstractNeuroscience is a technology‐driven discipline and brain energy metabolism is no exception. Once satisfied with mapping metabolic pathways at organ level, we are now looking to learn what it is exactly that metabolic enzymes and transporters do and when, where do they reside, how are they regulated, and how do they relate to the specific ...
L. Felipe Barros +11 more
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Early Life Stress and Metabolic Plasticity of Brain Cells: Impact on Neurogenesis and Angiogenesis
Biomedicines, 2021 Early life stress (ELS) causes long-lasting changes in brain plasticity induced by the exposure to stress factors acting prenatally or in the early postnatal ontogenesis due to hyperactivation of hypothalamic-pituitary-adrenal axis and sympathetic ...
Alla B. Salmina +5 more
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