Current technical approaches to brain energy metabolism. [PDF]
Glia, 2018 AbstractNeuroscience is a technology‐driven discipline and brain energy metabolism is no exception. Once satisfied with mapping metabolic pathways at organ level, we are now looking to learn what it is exactly that metabolic enzymes and transporters do and when, where do they reside, how are they regulated, and how do they relate to the specific ...
Barros LF +11 more
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Neuroglia and brain energy metabolism. [PDF]
Handb Clin NeurolThe glial control of energy homeostasis is of crucial importance for health and disease. Astrocytes in particular play a major role in controlling the equilibrium among adenosine 5'-triphosphate (ATP), adenosine 5'-diphosphate (ADP), adenosine 5'-monophosphate (AMP), and adenosine. Any energy crisis leads to a drop in ATP, and the resulting increase in
Peter-Okaka U, Boison D.
europepmc +3 more sources
Elucidating reaction dynamics in a model of human brain energy metabolism. [PDF]
PLoS Computational BiologyEnergy metabolism is essential to brain function and Bioinformatics, but its study is experimentally challenging. Similarly, biologically accurate computational models are too complex for simple investigations.
Dimitrios G Patsatzis +4 more
doaj +2 more sources
Pathology and Treatments of Alzheimer’s Disease Based on Considering Changes in Brain Energy Metabolism Due to Type 2 Diabetes [PDF]
MoleculesAlzheimer’s disease (AD) is a progressive neurodegenerative disorder with cognitive dysfunction, memory decline, and behavioral disturbance, and it is pathologically characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the ...
Hidekatsu Yanai +3 more
doaj +2 more sources
Brain energy metabolism: A roadmap for future research. [PDF]
J NeurochemAlthough we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so complex.
Rae CD +25 more
europepmc +4 more sources
GSK3β Regulates Brain Energy Metabolism. [PDF]
Cell Rep, 2018 GSK3β is a serine threonine kinase implicated in the progression of Alzheimer's disease. Although the role of GSK3β in growth and pathology has been extensively studied, little is known about the metabolic consequences of GSK3β manipulation, particularly in the brain.
Martin SA +8 more
europepmc +4 more sources
Brain Energy Metabolism in Two States of Mind Measured by Phosphorous Magnetic Resonance Spectroscopy [PDF]
Frontiers in Human Neuroscience, 2021 Introduction: Various functional neuroimaging studies help to better understand the changes in brain activity during meditation. The purpose of this study was to investigate how brain energy metabolism changes during focused attention meditation (FAM ...
Malik Galijašević +14 more
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Brain-acting hepatokines: its impact on energy balance and metabolism
Frontiers in NeuroscienceThe liver is recognized for its central role in energy metabolism, yet emerging evidence highlights its function as an endocrine organ, secreting a variety of proteins—hepatokines—that influence distant tissues.
Lucía Giovanini +4 more
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Editorial: Imaging brain network and brain energy metabolism impairments in brain disorders [PDF]
Frontiers in Molecular NeuroscienceYuhei Takado +2 more
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Effect of temperature and glia in brain size enlargement and origin of allometric body-brain size scaling in vertebrates [PDF]
, 2014 Background: Brain signaling requires energy. The cost of maintaining and supporting energetically demanding neurons is the key constraint on brain size.
Feng, Jianfeng +7 more
core +2 more sources