Results 41 to 50 of about 8,068,126 (191)

How Energy Metabolism Supports Cerebral Function: Insights from 13C Magnetic Resonance Studies In vivo

Frontiers in Neuroscience, 2017
Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream.
Sarah Sonnay, Rolf Gruetter, Rolf Gruetter, Rolf Gruetter, João M. N. Duarte   +4 more
doaj   +1 more source

Energy, Entropy and Quantum Tunneling of Protons and Electrons in Brain Mitochondria: Relation to Mitochondrial Impairment in Aging-Related Human Brain Diseases and Therapeutic Measures

Biomedicines, 2021
Adult human brains consume a disproportionate amount of energy substrates (2–3% of body weight; 20–25% of total glucose and oxygen). Adenosine triphosphate (ATP) is a universal energy currency in brains and is produced by oxidative phosphorylation ...
James P. Bennett, Isaac G. Onyango
doaj   +1 more source

Brain energy metabolism in streptozotocin-diabetes [PDF]

Biochemical Journal, 1988
Regional brain glucose use was measured in rats with streptozotocin-induced diabetes (65 mg/kg intravenously) of 1 or 4 weeks duration, by using [6-14C]glucose and quantitative autoradiography. The concentrations of several metabolites were measured in plasma and brain. Results were compared with those from normal untreated rats. Glucose concentrations
A M, Mans, M R, DeJoseph, D W, Davis, R A, Hawkins   +3 more
openaire   +2 more sources

Non-signalling energy use in the brain [PDF]

, 2015
Energy use limits the information processing power of the brain. However, apart from the ATP used to power electrical signalling, a significant fraction of the brain's energy consumption is not directly related to information processing. The brain spends
Attwell, D, Engl, E
core  

Autism as a brain energy disorder: How impairments in brain glucose metabolism give rise to autism symptoms

Brain Network Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental condition that is characterized by social communication deficits, restricted and repetitive behavioral patterns, and sensory abnormalities.
Natasa Blagojevic-Stokic, Paul Whiteley, Ben Marlow, Jane Wills   +3 more
doaj   +1 more source

Cerebrospinal fluid ATP metabolites in multiple sclerosis [PDF]

, 2010
Increased axonal energy demand and mitochondrial failure have been suggested as possible causes for axonal degeneration and disability in multiple sclerosis.Our objective was to test whether ATP depletion precedes clinical, imaging and biomarker evidence
Uitdehaag, BMJ, Di Pietro, V., Barkhof, F., Killestein, J, Belli, A.; id_orcid, Killestein, J., Uitdehaag, B.M.J., Eikelenboom, M.J., University of Catania, Tavazzi, B, Petzold, A.F.S., Petzold, A., Petzold, A, Belli, A., Eikelenboom, MJ, Lazzarino, G., Lazzarino, G, Di Pietro, V, Polman, CH, Amorini, A.M., Barkhof, F, Tavazzi, B., Polman, C.H., Belli, A, Di Pietro, V.; id_orcid, Amorini, AM, Pietro, V. Di   +26 more
core   +1 more source

Brain Mass (Energy) Resistant to Hyperglycaemic Oversupply: A Systematic Review

Frontiers in Neuroscience, 2021
Cerebral energy supply is determined by the energy content of the blood. Accordingly, the brain is undersupplied during hypoglycaemia. Whether or not there is an additional cerebral energy demand that depends upon the energy content of the brain is ...
Marie Sprengell, Britta Kubera, Achim Peters   +2 more
doaj   +1 more source

Timing of potential and metabolic brain energy [PDF]

Journal of Neurochemistry, 2007
AbstractThe temporal relationship between cerebral electro‐physiological activities, higher brain functions and brain energy metabolism is reviewed. The duration of action potentials and transmission through glutamate and GABA are most often less than 5 ms.
Korf, Jakob, Gramsbergen, Jan Bert
openaire   +3 more sources

Human neuromaturation, juvenile extreme energy liability, and adult cognition/cooperation [PDF]

, 2012
Human childhood and adolescence is the period in which adult cognitive competences (including those that create the unique cooperativeness of humans) are acquired.
John Skoyles
core  

Ketones and brain development: Implications for correcting deteriorating brain glucose metabolism during aging

Oilseeds and fats, crops and lipids, 2016
Brain energy metabolism in Alzheimer’s disease (AD) is characterized mainly by temporo-parietal glucose hypometabolism. This pattern has been widely viewed as a consequence of the disease, i.e.
Nugent Scott, Courchesne-Loyer Alexandre, St-Pierre Valerie, Vandenberghe Camille, Castellano Christian-Alexandre, Cunnane Stephen C.   +5 more
doaj   +1 more source