A model of brain circulation and metabolism: NIRS signal changes during physiological challenges [PDF]
We construct a model of brain circulation and energy metabolism. The model is designed to explain experimental data and predict the response of the circulation and metabolism to a variety of stimuli, in particular, changes in arterial blood pressure, CO2
Mallet, Alfred +18 more
core +2 more sources
Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]
Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
Teipel, S. J. +13 more
core +1 more source
Pursuing More Sustainable Consumption by Analyzing Household Metabolism in European Countries and Cities [PDF]
Bringing about more sustainable consumption patterns is an important challenge for society and science. In this article the concept of household metabolism is applied to analyzing consumption patterns and to identifying possibilities for the development ...
Clark, Charlotte, +24 more
core +2 more sources
Serotonergic Regulation of Hepatic Energy Metabolism [PDF]
The liver is a vital organ that regulates systemic energy metabolism and many physiological functions. Nonalcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease and end-stage liver failure.
윤차현 +4 more
core +1 more source
The brain is an organ that consumes a lot of energy. In the brain, energy is required for synaptic transmission, numerous biosynthetic processes and axonal transport in neurons, and for many supportive functions of glial cells.
Maria M. Bayliak +2 more
doaj +1 more source
Multivitamins and minerals modulate whole-body energy metabolism and cerebral blood-flow during cognitive task performance: a double-blind, randomised, placebo-controlled trial [PDF]
Background: The brain is by far the most metabolically active organ in the body, with overall energy expenditure and local blood-supply closely related to neural activity.
Jackson, Philippa A. +41 more
core +1 more source
Summary: Neutrophil aggregation and clearance are important factors affecting neuroinflammatory injury during acute ischemic stroke. Emerging evidence suggests that energy metabolism is essential for microglial functions, especially microglial ...
Lei Li +9 more
doaj +1 more source
Impairments in Oxidative Glucose Metabolism in Epilepsy and Metabolic Treatments Thereof
There is mounting evidence that oxidative glucose metabolism is impaired in epilepsy and recent work has further characterized the metabolic mechanisms involved.
Tanya McDonald +3 more
doaj +1 more source
Creatine protects against excitoxicity in an in vitro model of neurodegeneration. [PDF]
Creatine has been shown to be neuroprotective in aging, neurodegenerative conditions and brain injury. As a common molecular background, oxidative stress and disturbed cellular energy homeostasis are key aspects in these conditions. Moreover, in a recent
Geiger Johanna +17 more
core +1 more source
Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as short chain fatty acids (SCFAs). SCFAs have been proposed as a possible mechanism through which the gut
Tiffany A. Fillier +8 more
doaj +1 more source

