Results 21 to 30 of about 8,068,126 (191)

A model of brain circulation and metabolism: NIRS signal changes during physiological challenges [PDF]

open access: yes, 2008
We construct a model of brain circulation and energy metabolism. The model is designed to explain experimental data and predict the response of the circulation and metabolism to a variety of stimuli, in particular, changes in arterial blood pressure, CO2
Mallet, Alfred   +18 more
core   +2 more sources

Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]

open access: yes, 2005
Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
Teipel, S. J.   +13 more
core   +1 more source

Pursuing More Sustainable Consumption by Analyzing Household Metabolism in European Countries and Cities [PDF]

open access: yes, 2005
Bringing about more sustainable consumption patterns is an important challenge for society and science. In this article the concept of household metabolism is applied to analyzing consumption patterns and to identifying possibilities for the development ...
Clark, Charlotte,   +24 more
core   +2 more sources

Serotonergic Regulation of Hepatic Energy Metabolism [PDF]

open access: yes, 2021
The liver is a vital organ that regulates systemic energy metabolism and many physiological functions. Nonalcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease and end-stage liver failure.
윤차현   +4 more
core   +1 more source

Homeostasis of carbohydrates and reactive oxygen species is critically changed in the brain of middle-aged mice: Molecular mechanisms and functional reasons

open access: yesBBA Advances, 2023
The brain is an organ that consumes a lot of energy. In the brain, energy is required for synaptic transmission, numerous biosynthetic processes and axonal transport in neurons, and for many supportive functions of glial cells.
Maria M. Bayliak   +2 more
doaj   +1 more source

Multivitamins and minerals modulate whole-body energy metabolism and cerebral blood-flow during cognitive task performance: a double-blind, randomised, placebo-controlled trial [PDF]

open access: yes, 2016
Background: The brain is by far the most metabolically active organ in the body, with overall energy expenditure and local blood-supply closely related to neural activity.
Jackson, Philippa A.   +41 more
core   +1 more source

Resolvin D1 reprograms energy metabolism to promote microglia to phagocytize neutrophils after ischemic stroke

open access: yesCell Reports, 2023
Summary: Neutrophil aggregation and clearance are important factors affecting neuroinflammatory injury during acute ischemic stroke. Emerging evidence suggests that energy metabolism is essential for microglial functions, especially microglial ...
Lei Li   +9 more
doaj   +1 more source

Impairments in Oxidative Glucose Metabolism in Epilepsy and Metabolic Treatments Thereof

open access: yesFrontiers in Cellular Neuroscience, 2018
There is mounting evidence that oxidative glucose metabolism is impaired in epilepsy and recent work has further characterized the metabolic mechanisms involved.
Tanya McDonald   +3 more
doaj   +1 more source

Creatine protects against excitoxicity in an in vitro model of neurodegeneration. [PDF]

open access: yes, 2012
Creatine has been shown to be neuroprotective in aging, neurodegenerative conditions and brain injury. As a common molecular background, oxidative stress and disturbed cellular energy homeostasis are key aspects in these conditions. Moreover, in a recent
Geiger Johanna   +17 more
core   +1 more source

Brief exposure of neuronal cells to levels of SCFAs observed in human systemic circulation impair lipid metabolism resulting in apoptosis

open access: yesScientific Reports, 2022
Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as short chain fatty acids (SCFAs). SCFAs have been proposed as a possible mechanism through which the gut
Tiffany A. Fillier   +8 more
doaj   +1 more source

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