Results 71 to 80 of about 18,951,710 (338)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Do Caloric Test Results Affect the Prognosis of Sudden Hearing Loss?
, 2017 Aim: The aim of this study is to evaluate the prognostic value of caloric test results in patients with sudden hearing loss.Material -Method: We evaluated 23 patients with sudden hearing loss who were hospitalized.
Süha Beton, Muharrem Gerçeker
core +1 more source
Neotropical IchthyologyIn the present study we analysed the proximate-composition and caloric values of the preferred prey consumed by ribbonfish, Trichiurus lepturus L. 1758 (adult females), that are distributed in the inner continental shelf from northern Rio de Janeiro ...
Vanessa Trindade Bittar +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2018 Over the years, experimental and numerical studies have consolidated the potential of the caloric cooling as a technology of tomorrow. The numerous investigations conducted all-over-the-world have shown that the bottleneck in the energy performances of a
DEL DUCA M. G. +4 more
core +1 more source
Utilization of Yacon Damaged Roots as a Source of FOS-Enriched Sweet-Tasting Syrup
Applied SciencesDamaged yacon roots, often discarded, are a rich source of sweet carbohydrates. In this context, yacon roots from the Hualqui and Crespo varieties were characterized and processed into low-calorie and low-glycemic syrups for sugar reduction in foods ...
Pedro A. R. Fernandes +9 more
doaj +1 more source
Proximate food composition and caloric value of foods from animal origen
, 2000 Proximate food composition data are very important to any professionals of food science and human nutrition area. In Brazil they are rare or do not exist.
E. A. Ferraz da Silva Torres +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
A method of estimation of the caloric value of the biomass. Part I – biomass energy potential [PDF]
, 2017 KoszalinThe caloric value of the crops is one of the fundamental parameters to be determined during the process of biomass production for the energy purposes.
Piskier, Tomasz
core +3 more sources