Understanding Energy Expenditure: An Approach to Improving Activities of Daily Living in Huntington's Disease. [PDF]
Simón-Vicente L +6 more
europepmc +1 more source
Adipocyte‐specific NIK depletion enhances energy metabolism and glucose tolerance in mice
Obesity is associated with reduced energy expenditure and increased hepatic lipid accumulation. This study reveals that loss of NIK in adipocytes stimulates FGF21‐driven expression of thermogenic genes, including UCP1, and mitochondrial uncoupled respiration.
Atakan Ozcan +8 more
wiley +1 more source
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa +1 more
wiley +1 more source
Menopausal duration and relative skeletal muscle index predict metabolic inflexibility during walking in postmenopausal women with overweight/obesity. [PDF]
Blechschmid TH +5 more
europepmc +1 more source
Bio‐active designed peptide for hair keratin strengthening
Bioactive tripeptides through in silico screening revealed KCV (Tripeptide‐132) as the most promising keratin‐targeting candidate. Experimental studies confirmed its superior hair‐strengthening performance with 44% tensile strength enhancement, 50% breakage reduction, improved surface integrity and fibre penetration.
Chan‐Su Rha +6 more
wiley +1 more source
Validity of Galaxy Watch for Estimating Energy Expenditure During Intermittent Running: Cross-Sectional Study. [PDF]
Ferreira ARP +7 more
europepmc +1 more source
Frailty in Adults With Down Syndrome: Cognitive, Functional and Biomarker Associations
ABSTRACT Background Down syndrome (DS) entails widespread age‐related functional decline affecting multiple organ systems, including genetically determined early‐onset Alzheimer disease (DSAD), resulting in an increased vulnerability to frailty early in life.
Georg Nübling +11 more
wiley +1 more source
Six- and Twelve-Month Changes in Body Composition and 24-h Energy Expenditure After a Very Low-Calorie Ketogenic Diet. [PDF]
Basolo A +10 more
europepmc +1 more source
ABSTRACT Diet composition and processing have a major impact on its utilisation by the animal, as is known from farm and pet animal species. This includes effects on energy and nutrient digestibility, the intermediary metabolism, and the intestinal microbiome, with all the resulting impacts. For laboratory animals, data is scarce on influencing factors
L. F. Böswald +6 more
wiley +1 more source
Hepatic ketogenic insufficiency blunts exercise-induced energy expenditure and alters mitochondrial proteins in skeletal muscle. [PDF]
Davis XC +10 more
europepmc +1 more source

