Results 111 to 120 of about 4,120 (216)
GenBank: MK585065.1: Homo sapiens calpastatin (CAST) mRNA, complete cds
, 2019 Homo sapiens clone hcast 3-25 calpastatin (CAST) mRNA, complete. (GenBank: MK585065.1) This mRNA sequence refers to a human calpastatin transcript skipped of the inhibitory region detected in normal peripheral blood cells.
De Tullio R
core
Suppression of okadaic acid-induced apoptosis by overexpression of calpastatin in human UVr-1 cells
, 1999 Proteolytic systems have various involvements in apoptotic pathways. To understand the role of calpain in apoptosis, calpastatin, a specific inhibitor of calpain, was overexpressed in human UVr-1 fibroblasts by transfection of its cDNA.
Kita, Kazuko +13 more
core +1 more source
Genetic Polymorphisms of the Coding Region (Exon 6) of Calpastatin in Indonesian Sheep
Media Peternakan, 2011 Calpastatin (CAST) is an indigenous inhibitor of calpain that involved in regulation of protein turn over and growth. The objective of this research was to identify genetic polymorphisms in the entire exon 6 of calpastatin gene in Indonesian local sheep.
M. I. A. Dagong +4 more
doaj
The involvement of calpastatin in myoblast fusion
, 2000 Myoblast fusion is a dynamic event that can be recreated in vitro using tissue culture. Portions of cDNA encoding inhibitory and non-inhibitory domains of ovine calpastatin were expressed in murine C2C12 myoblasts as fusion proteins with enhanced green ...
Kent, Matthew P.
core
Variation in the Yak calpastatin gene (CAST)
, 2012 Calpastatin (CAST) is a specific inhibitor of calpain (calcium-dependent cysteine protease). This study investigated the potential for variation in yak (Bos grennies) CAST. PCR-SSCP analysis of exon 6 of yak CAST revealed three unique patterns (named A-C)
Hu, J +4 more
core +1 more source
Calpain and calpastatin in myoblast differentiation and fusion: Effects of inhibitors
, 1997 Myoblast differentiation and fusion to multinucleated muscle cells can be studied in myoblasts grown in culture. Calpain (Ca2+-activated thiol protease) induced proteolysis has been suggested to play a role in myoblast fusion.
Glaser, Tova +2 more
core +1 more source
Extracellular Calpain/Calpastatin Balance Is Involved in the Progression of Pulmonary Hypertension
, 2016 Excessive growth of pulmonary arterial (PA) smooth muscle cells (SMCs) is a major component of PA hypertension (PAH). The calcium-activated neutral cysteine proteases calpains 1 and 2, expressed by PASMCs, contribute to PH but are tightly controlled by a
Derumeaux, Genevieve +17 more
core +1 more source
Engineering Calpastatin to Develop a Sensor to Detect Active Calpain
, 2006 Calpains, Ca2+-activated cysteine proteases are essential for early embryonic development and function in signal transduction, cell adhesion, and apoptosis.
Vanhooser, Lisa M.
core
, 2013 The overall objective of the work in this dissertation was to characterize -calpain, m-calpain, and calpastatin activities in order to learn more about the system in the live animal as well as its potential effects on postmortem proteolysis.
Cruzen, Shannon
core