Results 91 to 100 of about 4,652 (211)

Rosetta predictions for experimentally tested calpain/calpastatin interface redesigns.

open access: yes, 2012
Calpain is shown in cyan and calpastatin is shown in magenta, with the calpastatin position shown in yellow. Rosetta predictions for calpastatin position 607, wild type serine (A), amino-butyeiric acid (B), norvaline (C).
Richard Bonneau (4318)   +3 more
core   +1 more source

Inducible expression of bovine calpastatin in C(2)C(12) mouse myoblasts and the relationship of restriction fragment length polymorphisms at the bovine calpastatin locus to postmortem calpastatin activity and Warner-Bratzler shear force in beef longissimus steaks

open access: yes, 1995
Two separate studies to define further the role of calpastatin in muscle growth and development and postmortem tenderization of meat were conducted. The objective of the first study was to determine if restriction fragment length polymorphisms (RFLP) at ...
Lonergan, Steven Michael
core   +1 more source

IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults.

open access: yesFrontiers in Cellular Neuroscience, 2013
Excitotoxicity is a major component of neurodegenerative diseases and is typically accompanied by an inflammatory response. Cytokines IL-1alpha and IL-1beta are key regulators of this inflammatory response and modulate the activity of numerous cell types,
David eGosselin   +2 more
doaj   +1 more source

Differences in skeletal muscle proteolysis in Nellore and Angus cattle might be driven by Calpastatin activity and not the abundance of Calpain/Calpastatin [PDF]

open access: yes, 2017
The present study aimed to explore the molecular factors underlying differences in Calpain/Calpastatin proteolytic system in Nellore and Angus cattle.
Duarte, M. S.   +15 more
core   +1 more source

PEST sequences in the malaria parasite Plasmodium falciparum: a genomic study

open access: yesMalaria Journal, 2003
Background Inhibitors of the protease calpain are known to have selectively toxic effects on Plasmodium falciparum. The enzyme has a natural inhibitor calpastatin and in eukaryotes is responsible for turnover of proteins containing short sequences ...
Bell Angus, Mitchell David
doaj   +1 more source

Differential tissue expression of a calpastatin isoform in Xenopus embryos

open access: yes, 2007
This study is aimed at demonstrating the role played by a calpastatin isoform (Xcalp3) in Xenopus embryos. A specific monoclonal antibody (mAb) was raised against a glutathione S-transferase (GST)-Xcalp3 fusion protein and characterized by immunoblotting
M. MAZZINI   +7 more
core   +1 more source

Structure of the active 27-residue fragment of human calpastatin [PDF]

open access: yes, 1991
A synthetic 27-residue peptide corresponding to exon 1B of the endogenous inhibitor calpastatin contains a well-conserved region and has an ability to inhibit the cysteine endopeptidase calpain specifically.
Atsuo Tamura   +15 more
core   +1 more source

KERAGAMAN GEN CALPASTATIN, CALPAIN 3 DAN MYOSTATIN PADA DOMBA DI UP3 JONGGOL

open access: yesJurnal Ilmu Pertanian Indonesia, 2012
The aim of this study was to identify the genetic polymorphisms of calpastatin (CAST), calpain 3 (CAPN3) and myostatin (MSTN) on local sheep at Jonggol Animal Science Teaching and Research Unit (JASTRU). A total number of 294 blood samples were collected
Cece Sumantri   +5 more
doaj  

Genetic Variation of Calpastation Gene of Indigenous Bali Cattle (Bos javanicus) in Indonesia

open access: yesHayati Journal of Biosciences, 2019
Calpastatin is one of gene markers affecting meat tenderness. The study aimed to evaluate genetic variation of calpastatin (CAST) gene of Bali cattle (Bos javanicus) in lndonesia.
Endang Tri Margawati   +3 more
doaj   +1 more source

Polymorphism in the ovine calpastatin gene

open access: yes, 1994
There is evidence that variation in the calpastatin gene exists among breeds of cattle. It has been suggested that such variation contributes to differences in muscle growth and postmortem conditioning of meat.
Couldrey, Christine
core  

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