Results 71 to 80 of about 2,875 (178)
Molecular Oncology, Volume 19, Issue 6, Page 1855-1875, June 2025.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Short communication: Analysis of polymorphisms in candidate’s genes for meat quality in Lidia cattle
Spanish Journal of Agricultural Research, 2016 The aim of this paper was to analyze the segregation of some polymorphisms in three genes (CAPN1, CAST and DGAT1) related to meat quality in the Lidia cattle breed and some of its main lineages.
Rocio Pelayo +3 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2013 Excitotoxicity is a major component of neurodegenerative diseases and is typically accompanied by an inflammatory response. Cytokines IL-1alpha and IL-1beta are key regulators of this inflammatory response and modulate the activity of numerous cell types,
David eGosselin +2 more
doaj +1 more source
PEST sequences in the malaria parasite
Malaria Journal, 2003 Background Inhibitors of the protease calpain are known to have selectively toxic effects on Plasmodium falciparum. The enzyme has a natural inhibitor calpastatin and in eukaryotes is responsible for turnover of proteins containing short sequences ...
Bell Angus, Mitchell David
doaj +1 more source
Genetic Variation of Calpastation Gene of Indigenous Bali Cattle (Bos javanicus) in Indonesia
Hayati Journal of Biosciences, 2019 Calpastatin is one of gene markers affecting meat tenderness. The study aimed to evaluate genetic variation of calpastatin (CAST) gene of Bali cattle (Bos javanicus) in lndonesia.
Endang Tri Margawati +3 more
doaj +1 more source
KERAGAMAN GEN CALPASTATIN, CALPAIN 3 DAN MYOSTATIN PADA DOMBA DI UP3 JONGGOL
Jurnal Ilmu Pertanian Indonesia, 2012 The aim of this study was to identify the genetic polymorphisms of calpastatin (CAST), calpain 3 (CAPN3) and myostatin (MSTN) on local sheep at Jonggol Animal Science Teaching and Research Unit (JASTRU). A total number of 294 blood samples were collected
Cece Sumantri +5 more
doaj
Applied SciencesMeat from cull dairy cows is often used for human consumption; it is well known that tenderness adds value to the market, and dairy cattle meat is usually undervalued.
Maria de los Angeles Robles-Mota +10 more
doaj +1 more source
Genetic Polymorphisms of the Coding Region (Exon 6) of Calpastatin in Indonesian Sheep
Media Peternakan, 2011 Calpastatin (CAST) is an indigenous inhibitor of calpain that involved in regulation of protein turn over and growth. The objective of this research was to identify genetic polymorphisms in the entire exon 6 of calpastatin gene in Indonesian local sheep.
M. I. A. Dagong +4 more
doaj