Results 61 to 70 of about 2,875 (178)
Analysis of Population Structure and Selection Signatures in Two Iraqi Fat‐Tailed Sheep Breeds
Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.Awassi sheep exhibit clear genetic separation, whereas Hamdani sheep show an admixed profile, with iHS, ROH and Tajima's D analyses identifying breed‐specific candidate genes. Enrichment in immune response, hormone regulation and cellular signalling pathways highlights adaptive evolution and guides future breeding and conservation.
Mervan Bayraktar +6 more
wiley +1 more source
Animal Production: Indonesian Journal of Animal Production, 2012 . The purpose of research was to investigate whether there was influence of the addition of concentrates in basal feed on meat tenderness and calpastatin and calpain activities of three muscles of Kejobong does.
M Socheh +3 more
doaj
British Journal of Pharmacology, Volume 182, Issue 17, Page 4103-4121, September 2025.Abstract Background and Purpose Treatment of cancer patients with anthracyclines is known to cause dose‐dependent cardiotoxicity through several mechanisms including enhanced oxidative stress, ultimately resulting in defective excitation–contraction coupling.
Wesam Bassiouni +9 more
wiley +1 more source
Czech Journal of Animal Science, 2013 Frequencies of two SNPs in the μ-calpain (CAPN1) and calpastatin (CAST) genes in local and foreign commercial cross-breeds used in south-western Spain (Charolais, Limousin, and Retinta) were evaluated and the association of these markers with texture ...
C. Avilés +5 more
doaj +1 more source
Acta Physiologica, Volume 241, Issue 8, August 2025.ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source
Animals, 2019 Previous studies demonstrated that polymorphisms in the μ-calpain (CAPN1) and calpastatin (CAST) genes had significant effects on meat tenderness in different cattle populations.
Hyo Jun Lee +8 more
doaj +1 more source
Calpains and Calpastatin in Human Blood Platelets
Platelets, 1995 Calpain, a Ca(2+) activated intracellular protease and its endogeneous protein inhibitor, calpastatin are abundant in platelets. The structure and enzymological properties of calpain, including its isozymes, and of calpastatin in platelets have been fully characterized.
H, Ariyoshi, J, Kambayashi, M, Sakon
openaire +2 more sources
Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection
Advanced Science, Volume 12, Issue 25, July 3, 2025.The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng +10 more
wiley +1 more source
Calpain mediates epithelial cell microvillar effacement by enterohemorrhagic Escherichia coli
Frontiers in Microbiology, 2011 A member of the attaching and effacing (AE) family of pathogens, enterohemorrhagic Escherichia coli (EHEC) induces dramatic changes to the intestinal cell cytoskeleton, including effacement of microvilli.
YuShuan eLai +5 more
doaj +1 more source
Immunity and neuroinflammation in early stages of life and epilepsy
Epilepsia, Volume 66, Issue 7, Page 2157-2169, July 2025.Abstract The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy.
Angelica Vega García +5 more
wiley +1 more source