Results 41 to 50 of about 4,120 (216)

Clinical severity of β-thalassaemia/Hb E disease is associated with differential activities of the calpain-calpastatin proteolytic system. [PDF]

open access: yesPLoS ONE, 2012
Earlier observations in the literature suggest that proteolytic degradation of excess unmatched α-globin chains reduces their accumulation and precipitation in β-thalassaemia erythroid precursor cells and have linked this proteolytic degradation to the ...
Suriyan Sukati   +8 more
doaj   +1 more source

Connecting Heat Tolerance and Tenderness in Bos indicus Influenced Cattle

open access: yesAnimals, 2022
Bos indicus cattle are widely utilized in tropical and subtropical climates. Their heat tolerance and parasite resistance are integral for beef production in these regions; however, a reputation for excitable temperaments, slower growth, and variation in
Tracy L. Scheffler
doaj   +1 more source

Pin1 Promotes Regulated Necrosis Induced by Glutamate in Rat Retinal Neurons via CAST/Calpain2 Pathway

open access: yesFrontiers in Cellular Neuroscience, 2018
The purpose of the current study was to investigate whether peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (Pin1) can interact with calpastatin (CAST) and regulate CAST/calpain2, under excessive glutamate conditions, and subsequently regulate ...
Shuchao Wang   +12 more
doaj   +1 more source

Effect of postmortem storage on shear force value and calpain/calpastatin activity in longissimus dorsi muscle of rusa deer (cervus timorensis) [PDF]

open access: yesMATEC Web of Conferences, 2018
The objective of this study was to determine the effects of aging period on shear force values and activities of calpain/calpastatin enzymes of the longissimus dorsi (LD) muscle from rusa deer (Cervus timorensis).
Jantasaeng Orapin   +2 more
doaj   +1 more source

Polymorphism of the ovine calpastatin gene

open access: yesMolecular and Cellular Probes, 2007
Calpastatin is a specific inhibitor of calpains and has been implicated in the regulation of beef tenderization. Variation in the ovine calpastatin gene (CAST) was investigated by amplification of a fragment containing the entire exon 6 using polymerase chain reaction (PCR), followed by single-strand conformational polymorphism (PCR-SSCP) analysis and ...
H, Zhou, J G H, Hickford, H, Gong
openaire   +2 more sources

Influence of vitamins A, D3 and E status on post-mortem meat quality in steers under winter housing or pasture finishing systems

open access: yesAnimal, 2011
We investigated the influence of Swedish recommended vitamins A, D3 and E supplementation levels on muscle tenderness and fatty acid (FA) composition under indoor or outdoor finishing programmes.
T. Turner   +6 more
doaj   +1 more source

Binding of calpain fragments to calpastatin

open access: yesJournal of Biological Chemistry, 1991
Their cDNA-derived amino acid sequences predict that the 80-kDa subunits of the micromolar and millimolar Ca(2+)-requiring forms of the Ca(2+)-dependent proteinase (mu- and m-calpain, respectively) each consist of four domains and that the 28-kDa subunit common to both mu- and m-calpain consists of two domains.
T, Nishimura, D E, Goll
openaire   +2 more sources

Molecular analysis of ovine calpastatin (CAST) and myostatin (MSTN) genes in Synthetic Population Bulgarian Milk sheep using PCR-RFLP [PDF]

open access: yesJournal of BioScience and Biotechnology, 2015
The aim of present study was to investigate the polymorphism of calpastatin and myostatin genes in sheep from Synthetic Population Bulgarian Milk (SPBM) breed because they are considered as candidate genes for meat and growth traits.
SVETLANA GEORGIEVA   +4 more
doaj  

Genetic markers in sheep meat breeding

open access: yesВавиловский журнал генетики и селекции, 2016
Cattle breeding, including sheep farming, is an important sector of agriculture. Increasing productivity and improving meat quality are considered today as the priorities in the industry.
A. V. Deykin   +4 more
doaj   +1 more source

Activation of Calpain Contributes to Mechanical Ventilation-Induced Depression of Protein Synthesis in Diaphragm Muscle

open access: yesCells, 2022
Mechanical ventilation (MV) is a clinical tool that provides respiratory support to patients unable to maintain adequate alveolar ventilation on their own.
Hayden W. Hyatt   +3 more
doaj   +1 more source

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