Results 41 to 50 of about 2,875 (178)

Molecular analysis of ovine calpastatin (CAST) and myostatin (MSTN) genes in Synthetic Population Bulgarian Milk sheep using PCR-RFLP [PDF]

Journal of BioScience and Biotechnology, 2015
The aim of present study was to investigate the polymorphism of calpastatin and myostatin genes in sheep from Synthetic Population Bulgarian Milk (SPBM) breed because they are considered as candidate genes for meat and growth traits.
SVETLANA GEORGIEVA, DEYANA HRISTOVA, IVONA DIMITROVA, NEVYANA STANCHEVA, MILENA BOZHILOVA-SAKOVA   +4 more
doaj  

Genetic markers in sheep meat breeding

Вавиловский журнал генетики и селекции, 2016
Cattle breeding, including sheep farming, is an important sector of agriculture. Increasing productivity and improving meat quality are considered today as the priorities in the industry.
A. V. Deykin, M. I. Selionova, A. Yu. Krivoruchko, D. V. Kovalenko, V. I. Truhachev   +4 more
doaj   +1 more source

Calpain‐4 Knockdown Modulates Cholesterol Metabolism and LXRα Nuclear Localization in Experimental Alcohol‐Related Liver Disease

Alcohol, Clinical and Experimental Research, Volume 50, Issue 6, June 2026.
Calpain‐4 knockdown in alcohol‐related liver disease promotes LXRα nuclear translocation and HMGCR cleavage, enhancing cholesterol efflux via upregulation of ABCA1/ABCG1 and CPT‐1. This mechanism reduces hepatic cholesterol accumulation and microvesicular steatosis without affecting triglycerides or inflammatory markers, identifying calpain‐4 as a ...
Noriko Kitano, Jiang Li, Sam Taborski, Charis‐Marie Vanderpuye, Pooja Muddasani, Sudrishti Chaudhary, Jia‐Jun Liu, Silvia Liu, Juliane I. Beier, Josepmaria Argemi, Ramon Bataller, Gavin E. Arteel   +11 more
wiley   +1 more source

Ryanodine Receptor Ca2+ Leak‐Induced Redistribution of Ca2+ in Dystrophic mdx Mouse Muscle

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The dystrophic mdx mouse is a widely used model of Duchenne muscular dystrophy. Altered Ca2+ handling is a key feature, including increased Ca2+ leak through the ryanodine receptor (RyR1's), the primary Ca2+ release channel in skeletal muscle. Such leak has important downstream consequences for intracellular Ca2+ homeostasis.
Rhayanna B. Gaglianone, Cedric R. Lamboley, Taylor Dick, Aldo Meizoso‐Huesca, Daniel P. Singh, Bradley S. Launikonis   +5 more
wiley   +1 more source

Connecting Heat Tolerance and Tenderness in Bos indicus Influenced Cattle

Animals, 2022
Bos indicus cattle are widely utilized in tropical and subtropical climates. Their heat tolerance and parasite resistance are integral for beef production in these regions; however, a reputation for excitable temperaments, slower growth, and variation in
Tracy L. Scheffler
doaj   +1 more source

TAK1 Regulates Skeletal Muscle Mass, Hypertrophic Signaling, and Metabolic Homeostasis in Male and Female Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Targeted inactivation of TAK1 induces more rapid muscle atrophy in male mice compared to female mice. In addition, loss of TAK1 impairs mechanical overload–induced phosphorylation of p70S6K and rpS6, leading to blunted muscle hypertrophic growth. TAK1 inactivation also promotes lipid accumulation while reducing fatty acid metabolism in skeletal muscle ...
Meiricris Tomaz da Silva, Aniket S. Joshi, Anirban Roy, Troy A. Hornberger, Ashok Kumar   +4 more
wiley   +1 more source

Identification of Calpain Substrates by ORF Phage Display

Molecules, 2011
Substrate identification is the key to defining molecular pathways or cellular processes regulated by proteases. Although phage display with random peptide libraries has been used to analyze substrate specificity of proteases, it is difficult to deduce ...
Wei Li, Gabriela Alvarado, Nora B. Caberoy   +2 more
doaj   +1 more source

From Assessment to Optimization: A Comprehensive Review of the Mutton Quality Evaluation Index, Factors, and Improvement Strategies

Food Frontiers, Volume 7, Issue 3, May 2026.
This graphical abstract summarizes the comprehensive framework of mutton quality, including evaluation indices, influencing factors, and improvement strategies. Meat quality is systematically assessed through multiple dimensions, including flavor, color, pH, tenderness, water‐holding capacity, intramuscular fat, and nutritional composition.
Man‐yu Liu, Yi‐chen Jian, Fang Wang, Long‐xian Zhang, Sen‐yang Li, Shu‐cheng Huang, Fu‐chun Jian   +6 more
wiley   +1 more source

Calpastatin in erythrocytes of young and old individuals [PDF]

Biochemical Journal, 1994
To gain knowledge about the behaviour of calpastatin (the specific inhibitor of the Ca(2+)-dependent thiol protease calpain) in the intact cell, we analysed the inhibitor by specific antibodies and determined its activity in erythrocytes from individuals 20-34 years old (young) and 70-93 years old (old).
N, Schwarz-Benmeir, T, Glaser, S, Barnoy, N S, Kosower   +3 more
openaire   +2 more sources

Properties of calpastatin forms in rat brain [PDF]

FEBS Letters, 1998
Four recombinant calpastatin forms, deduced from rat brain mRNAs and differing in the number of inhibitory repetitive domains from zero to four, were expressed and characterized for their inhibitory efficiency on μ‐ and m‐calpain. Although the most effective one is a truncated calpastatin form composed of the N‐terminal region (domain L) and a single ...
MELLONI, EDON, DE TULLIO, ROBERTA, AVERNA, MONICA, TEDESCO I, SALAMINO, FRANCA, SPARATORE, BIANCA, PONTREMOLI, SANDRO   +6 more
openaire   +3 more sources