Results 41 to 50 of about 4,652 (211)
The calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma. [PDF]
PLoS ONE, 2013 Conventional calpains are ubiquitous cysteine proteases whose activity is promoted by calcium signaling and specifically limited by calpastatin. Calpain expression has been shown to be increased in human malignant cells, but the contribution of the ...
Quentin Raimbourg +7 more
doaj +1 more source
Polymorphism of the ovine calpastatin gene
Molecular and Cellular Probes, 2007 Calpastatin is a specific inhibitor of calpains and has been implicated in the regulation of beef tenderization. Variation in the ovine calpastatin gene (CAST) was investigated by amplification of a fragment containing the entire exon 6 using polymerase chain reaction (PCR), followed by single-strand conformational polymorphism (PCR-SSCP) analysis and ...
H, Zhou, J G H, Hickford, H, Gong
openaire +2 more sources
Animal, 2011 We investigated the influence of Swedish recommended vitamins A, D3 and E supplementation levels on muscle tenderness and fatty acid (FA) composition under indoor or outdoor finishing programmes.
T. Turner +6 more
doaj +1 more source
Calpastatin participates in the regulation of cell migration in BAP1-deficient uveal melanoma cells [PDF]
International Journal of Ophthalmology, 2019 AIM: To detect how BRCA-associated protein 1 (BAP1) regulates cell migration in uveal melanoma (UM) cells. METHODS: Wound healing and transwell assays were performed to detect UM cell migration abilities.
Han Yue +5 more
doaj +1 more source
Binding of calpain fragments to calpastatin
Journal of Biological Chemistry, 1991 Their cDNA-derived amino acid sequences predict that the 80-kDa subunits of the micromolar and millimolar Ca(2+)-requiring forms of the Ca(2+)-dependent proteinase (mu- and m-calpain, respectively) each consist of four domains and that the 28-kDa subunit common to both mu- and m-calpain consists of two domains.
T, Nishimura, D E, Goll
openaire +2 more sources
Study on genetic structure of CAST gene by PCR- SSCP method and its association with growth traits in lori-Bakhtiari sheep breed [PDF]
مجله بیوتکنولوژی کشاورزی, 2014 In this study, a 254 bp fragment containing exon 6 and a part of introns 5 and 6 of ovine CAST gene were amplified in 169 Lori-Bakhtiari lamb from Lori-Bakhtiari sheep breeding station by polymerase chain reactions.
Mohsen Ali +3 more
doaj +1 more source
Genetic markers in sheep meat breeding
Вавиловский журнал генетики и селекции, 2016 Cattle breeding, including sheep farming, is an important sector of agriculture. Increasing productivity and improving meat quality are considered today as the priorities in the industry.
A. V. Deykin +4 more
doaj +1 more source
Molecular analysis of ovine calpastatin (CAST) and myostatin (MSTN) genes in Synthetic Population Bulgarian Milk sheep using PCR-RFLP [PDF]
Journal of BioScience and Biotechnology, 2015 The aim of present study was to investigate the polymorphism of calpastatin and myostatin genes in sheep from Synthetic Population Bulgarian Milk (SPBM) breed because they are considered as candidate genes for meat and growth traits.
SVETLANA GEORGIEVA +4 more
doaj
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Cell Biology International, Volume 50, Issue 10, October 2026.ABSTRACT Myoblast differentiation is a crucial step of skeletal muscle regeneration and is impaired in the absence of the β2 adrenoceptor (ADRβ2). Since miR‐374b and miR‐326 regulate cell differentiation, this study investigated if ADRβ2 regulates myoblast differentiation via miR‐374b‐5p and miR‐326‐3p. Primary myoblasts from ADRβ2 knockout (β2KO) mice
Tatiana E. Koike +10 more
wiley +1 more source