META-Analysis of the Relationship Between c.282C>G Polymorphism of the CAST Gene and Meat Quality Traits of Cattle. [PDF]
This meta‐analysis confirms a significant association between the c.282C>G polymorphism of the CAST gene and meat quality traits in cattle, highlighting the potential of the C allele and GC genotype in genetic selection for improved tenderness and meat characteristics.
Dincel D, Uzabaci E.
europepmc +2 more sources
Feeding strategies and ageing time alter calpain system proteins activities and meat quality of Braford steers [PDF]
Objective The aim of this study was to evaluate the effect of ageing and feeding strategies on the calpain protease system and meat quality traits in Braford steers.
María Sumampa Coria +3 more
doaj +1 more source
The β2-Subunit of Voltage-Gated Calcium Channels Regulates Cardiomyocyte Hypertrophy
L-type voltage-gated calcium channels (LTCCs) regulate crucial physiological processes in the heart. They are composed of the Cavα1 pore-forming subunit and the accessory subunits Cavβ, Cavα2δ, and Cavγ. Cavβ is a cytosolic protein that regulates channel
Simone Pickel +17 more
doaj +1 more source
Meat quality, post-mortem proteolytic enzymes, and myosin heavy chain isoforms of different Thai native cattle muscles [PDF]
Objective This study investigated the meat quality characteristics, endogenous proteolytic enzymes, collagen content, and myosin heavy chain (MyHC) isoforms of different muscles of Thai native cattle (TNC).
Chanporn Chaosap +7 more
doaj +1 more source
Inhibition of human mu-calpain by conformationally constrained calpastatin peptides [PDF]
Pfizer J, Assfalg-Machleidt I, Machleidt W, Schaschke N. Inhibition of human mu-calpain by conformationally constrained calpastatin peptides. BIOLOGICAL CHEMISTRY.
Machleidt, Werner +3 more
core +1 more source
Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin [PDF]
Gil-Parrado S, Assfalg-Machleidt I, Fiorino F, et al. Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin. BIOLOGICAL CHEMISTRY.
Dominga Deluca +25 more
core +1 more source
Critical Roles of Calpastatin in Ischemia/Reperfusion Injury in Aged Livers
Ischemia/reperfusion (I/R) injury unavoidably occurs during hepatic resection and transplantation. Aged livers poorly tolerate I/R during surgical treatment.
Joseph Flores-Toro +9 more
doaj +1 more source
Is the expression of [-G93A(+)] human SOD1 a model to study neurodegenerations?
To relate the alterations occurring in neurodegenerations with Ca2+ homeostasis dysregulation, we analyzed the functional properties of the Ca2+-dependent calpain/calpastatin system in neuronal cells of transgenic mice overexpressing human mutated -G93A(+
R. Stifanese +6 more
doaj +1 more source
Calpastatin Subdomains A and C Are Activators of Calpain [PDF]
The inhibitory domains of calpastatin contain three highly conserved regions, A, B, and C, of which A and C bind calpain in a strictly Ca(2+)-dependent manner but have no inhibitory activity whereas region B inhibits calpain on its own. We synthesized the 19-mer oligopeptides corresponding to regions A and C of human calpastatin domain I and tested ...
Tompa, P +3 more
openaire +3 more sources
The calpastatin-derived calpain inhibitor CP1B reduces mRNA expression of matrix metalloproteinase-2 and-9 and invasion by leukemic THP-1 cells [PDF]
The ubiquitous proteases μ- and m-calpain are Ca2+-dependent cysteine endopeptidases. Besides involvement in a variety of physio(patho)logical processes, recent studies suggest a pivotal role of calpains in differentiation of hematopoietic cells and ...
Ries, C. +5 more
core +1 more source

